Evidence map›Paper›PMID 30505029›Full record

ArticleBulletin of the World Health Organization2018

Oral cholera vaccination in hard-to-reach communities, Lake Chilwa, Malawi.

Francesco Grandesso, Florentina Rafael, Sikhona Chipeta, Ian Alley, Christel Saussier, Francisco Nogareda, Monica Burns, Pauline Lechevalier, Anne-Laure Page, Leon Salumu and 6 more

Abstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Francesco GrandessoEpicentre, 8 rue Saint-Sabin, 75011 Paris, France.
Florentina RafaelAgence de Médecine Préventive, Paris, France.
Sikhona ChipetaDirectorate of Preventive Health Services, Ministry of Health, Lilongwe, Malawi.
Ian AlleyEpicentre, 8 rue Saint-Sabin, 75011 Paris, France.
Christel SaussierAgence de Médecine Préventive, Paris, France.
Francisco NogaredaDepartment of Infectious Hazard Management, World Health Organization, Geneva, Switzerland.
Monica BurnsMédecins Sans Frontières, Paris, France.
Pauline LechevalierMédecins Sans Frontières, Paris, France.
Anne-Laure PageEpicentre, 8 rue Saint-Sabin, 75011 Paris, France.
Leon SalumuMédecins Sans Frontières, Paris, France.
Lorenzo PezzoliDepartment of Infectious Hazard Management, World Health Organization, Geneva, Switzerland.
Maurice MwesawinaDirectorate of Preventive Health Services, Ministry of Health, Lilongwe, Malawi.
Philippe CavaillerAgence de Médecine Préventive, Paris, France.
Martin MengelAgence de Médecine Préventive, Paris, France.
Francisco Javier LuqueroEpicentre, 8 rue Saint-Sabin, 75011 Paris, France.
Sandra CohuetEpicentre, 8 rue Saint-Sabin, 75011 Paris, France.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveTo evaluate vaccination coverage, identify reasons for non-vaccination and assess satisfaction with two innovative strategies for distributing second doses in an oral cholera vaccine campaign in 2016 in Lake Chilwa, Malawi, in response to a cholera outbreak.

methodsWe performed a two-stage cluster survey. The population interviewed was divided in three strata according to the second-dose vaccine distribution strategy: (i) a standard strategy in 1477 individuals (68 clusters of 5 households) on the lake shores; (ii) a simplified cold-chain strategy in 1153 individuals (59 clusters of 5 households) on islands in the lake; and (iii) an out-of-cold-chain strategy in 295 fishermen (46 clusters of 5 to 15 fishermen) in floating homes, called FINDING: Vaccination coverage with at least one dose was 79.5% (1153/1451) on the lake shores, 99.3% (1098/1106) on the islands and 84.7% (200/236) on

conclusionVaccination coverage on the shores of Lake Chilwa was moderately high and the innovative distribution strategies tailored to people living on the lake provided adequate coverage, even among hard-to-reach communities. Community engagement and simplified delivery procedures were critical for success. Off-label, out-of-cold-chain administration of oral cholera vaccine should be considered as an effective strategy for achieving high coverage in hard-to-reach communities. Nevertheless, coverage and effectiveness must be monitored over the short and long term.

Indexed as

Administration, OralAdolescentChildChild, PreschoolCholeraCholera VaccinesFemaleHumansInfantInterviews as TopicMalawiMaleQualitative ResearchVaccination CoverageCholera Vaccines

Identifiers

PMID30505029
PMCPMC6249704

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.