ArticleScientific reports2018
Developmental trajectory of movement-related cortical oscillations during active sleep in a cross-sectional cohort of pre-term and full-term human infants.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 28 citations in OpenAlex.
- Twitching in sleeping premature infants provides a sensitive behavioral assay of early motor control.iScience · 2026Article
- Twitching in sleeping premature infants provides a sensitive behavioral assay of early motor control.bioRxiv : the preprint server for biology · 2026Article
- The impact of sleep in high-risk infants.Pediatric research · 2025Review
- Co-developing sleep-wake and sensory foundations for cognition in the human fetus and newborn.Developmental cognitive neuroscience · 2025Review
- More Than a Small Brain: The Importance of Studying Neural Function during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Sleep as a driver of pre- and postnatal brain development.Pediatric research · 2024Review
- Spatiotemporal patterns of spontaneous movement in neonates are significantly linked to risk of autism spectrum disorders at 18 months old.Scientific reports · 2023Article
- Sleep, plasticity, and sensory neurodevelopment.Neuron · 2022Review
- Review
- Prognostic value of neonatal EEG following therapeutic hypothermia in survivors of hypoxic-ischemic encephalopathy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles.Current biology : CB · 2021Article
- The Radically Embodied Conscious Cybernetic Bayesian Brain: From Free Energy to Free Will and Back Again.Entropy (Basel, Switzerland) · 2021Article
- Article
- Spatiotemporal organization of myoclonic twitching in sleeping human infants.Developmental psychobiology · 2020Article
- THE DEVELOPING BRAIN REVEALED DURING SLEEP.Current opinion in physiology · 2020Article
- Dance on the Brain: Enhancing Intra- and Inter-Brain Synchrony.Frontiers in human neuroscience · 2020Article
- Long-range temporal organisation of limb movement kinematics in human neonates.Clinical neurophysiology practice · 2020Article
- Event-related potentials following contraction of respiratory muscles in pre-term and full-term infants.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- Dynamic touch reduces physiological arousal in preterm infants: A role for c-tactile afferents?Developmental cognitive neuroscience · 2019Article
- Fronto-central slow cortical activity is attenuated during phasic events in rapid eye movement sleep at full-term birth.Early human development · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In neonatal animal models, isolated limb movements during active sleep provide input to immature somatomotor cortex necessary for its development and are somatotopically encoded by alpha-beta oscillations as late as the equivalent of human full-term. Limb movements elicit similar neural patterns in very pre-term human infants (average 30 corrected gestational weeks), suggesting an analogous role in humans, but it is unknown until when they subserve this function. In a cohort of 19 neonates (31-42 corrected gestational weeks) we showed that isolated hand movements during active sleep continue to induce these same somatotopically distributed oscillations well into the perinatal period, but that these oscillations decline towards full-term and fully disappear at 41 corrected gestational weeks (equivalent to the end of gestation). We also showed that these highly localised alpha-beta oscillations are associated with an increase in delta oscillations which extends to the frontal area and does not decline with age. These results suggest that isolated limb movements during active sleep could have an important role in experience-dependent somatomotor development up until normal birth in humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.