ArticleNature communications2018
Nanoribbons self-assembled from short peptides demonstrate the formation of polar zippers between β-sheets.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 115 citations in OpenAlex.
- Topology-Encoded Charge Polarity Governs Multiphase Organization in Intrinsically Disordered Protein Polymer Condensates.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Poly(L-Tyrosine)-Containing Dehydropeptides: Hydrogels vs. Bioadhesives.Gels (Basel, Switzerland) · 2026Article
- Ligand Side-Chains Control the Formation of an MInorganic chemistry · 2026Article
- Advances in Biomaterials Development and Their Energy Harvesting Application.Research (Washington, D.C.) · 2026Review
- Exploring the temperature dependence of β-hairpin peptide self-assembly.Faraday discussions · 2025Article
- Influence of Electrostatic Interactions on the Self-Assembly of Charged Peptides.Gels (Basel, Switzerland) · 2025Article
- Construction of Targeting-Peptide-Based Imaging Reagents and Their Application in Bioimaging.Chemical & biomedical imaging · 2024Review
- Self-assembled short peptides: Recent advances and strategies for potential pharmaceutical applications.Materials today. Bio · 2023Review
- Controlling the Self-Assembly and Material Properties of β-Sheet Peptide Hydrogels by Modulating Intermolecular Interactions.Gels (Basel, Switzerland) · 2023Article
- Unsupervised Data-Driven Reconstruction of Molecular Motifs in Simple to Complex Dynamic Micelles.The journal of physical chemistry. B · 2023Article
- Amyloid-Gold Nanoparticle Hybrids for Biocompatible Memristive Devices.Materials (Basel, Switzerland) · 2023Article
- Detecting the Hydrogen Bond Cooperativity in a Protein β-Sheet by H/D Exchange.International journal of molecular sciences · 2022Article
- Dendritic Self-assembled Structures from Therapeutic Charged Pentapeptides.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Statistics and topology of fluctuating ribbons.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Bioinspired supramolecular nanofiber hydrogel through self-assembly of biphenyl-tripeptide for tissue engineering.Bioactive materials · 2022Article
- Self-Assembly of Short Amphiphilic Peptides and Their Biomedical Applications.Current pharmaceutical design · 2022Review
- General Principles Underpinning Amyloid Structure.Frontiers in neuroscience · 2022Review
- From structure to application: Progress and opportunities in peptide materials development.Current opinion in chemical biology · 2021Review
- Capacity for increased surface area in the hydrophobic core of β-sheet peptide bilayer nanoribbons.Journal of peptide science : an official publication of the European Peptide Society · 2021Article
- Peptide-Assisted Nucleic Acid Delivery Systems on the Rise.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peptide self-assembly is a hierarchical process, often starting with the formation of α-helices, β-sheets or β-hairpins. However, how the secondary structures undergo further assembly to form higher-order architectures remains largely unexplored. The polar zipper originally proposed by Perutz is formed between neighboring β-strands of poly-glutamine via their side-chain hydrogen bonding and helps to stabilize the sheet. By rational design of short amphiphilic peptides and their self-assembly, here we demonstrate the formation of polar zippers between neighboring β-sheets rather than between β-strands within a sheet, which in turn intermesh the β-sheets into wide and flat ribbons. Such a super-secondary structural template based on well-defined hydrogen bonds could offer an agile route for the construction of distinctive nanostructures and nanomaterials beyond β-sheets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.