Evidence map›Paper›PMID 30504363›Full record

ArticleGenetics2019

The Genetic Basis of Mutation Rate Variation in Yeast.

Liangke Gou, Joshua S Bloom, Leonid Kruglyak

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 58 citations in OpenAlex.

  1. Dynamics of mutators of arbitrary dominance in humans.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. What Has Genomics Taught An Evolutionary Biologist?Genomics, proteomics & bioinformatics · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Liangke GouDepartment of Human Genetics, University of California, Los Angeles, California 90095.ORCID 0000-0002-5767-9603
Joshua S BloomDepartment of Human Genetics, University of California, Los Angeles, California 90095.ORCID 0000-0002-7241-1648
Leonid KruglyakDepartment of Human Genetics, University of California, Los Angeles, California 90095 lkruglyak@mednet.ucla.edu.ORCID 0000-0002-8065-3057
Howard Hughes Medical Institute · USUniversity of California, Los Angeles · US

Funding

Toward comprehensive genetic dissection of complex traits in yeastR01GM102308 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEONID KRUGLYAK · 2012 to 2026
$3.3M
NIGMS NIH HHS R01 GM102308
6 · The paper itself

Abstract

Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis of these differences. Here, we leveraged the power of the yeast

Indexed as

Genetic VariationMutation RateDNA HelicasesGenetic LinkageQuantitative Trait LociSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA HelicasesMKT1 protein, S cerevisiaeRAD5 protein, S cerevisiaeSaccharomyces cerevisiae Proteinscomplex traitsgenetic basisnatural variantsQTL mappingSpontaneous mutation rateyeast

Identifiers

PMID30504363
PMCPMC6366923
OpenAlexW2950354887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.