Evidence map›Paper›PMID 30504303›Full record

ReviewHematology. American Society of Hematology. Education Program2018

Long-term complications in adolescent and young adult leukemia survivors.

K Scott Baker, Karen L Syrjala

Abstract readReview
In one paragraph

Review in Hematology. American Society of Hematology. Education Program, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pregnancy after cancer: FIGO Best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. BMJ open · 2026
    Article
  8. How young cancer patients cope with death anxiety: a qualitative study based on terror management theory.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Bridging gaps in cancer care for young adults: A collaborative e-learning initiative for oncology nurses.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Beyond depression: correlates of well-being in young adult survivors of childhood cancers.Journal of cancer survivorship : research and practice · 2023
    Article
  19. Article
  20. Disparities in physical activity in adolescent and young adult cancer survivors.Journal of cancer survivorship : research and practice · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

K Scott BakerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Karen L SyrjalaClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
Couple Communication in Cancer: A Multi-Method Examination - Renewal - 1R01CA201179 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Shelby Langer, LAURA S PORTER · 2016 to 2026
$7.2M
Improving treatment of cardiovascular risk factors in childhood cancer survivorsR01CA204378 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI CHOW, ERIC JESSEN · 2017 to 2021
$3.7M
Integrating health informatics in a scalable stepped care self-management program for survivors after hematopoietic cell transplantationR01CA215134 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S, MAJHAIL, NAVNEET S. · 2017 to 2022
$3.6M
NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA201179NCI NIH HHS R01 CA204378NCI NIH HHS R01 CA215134
6 · The paper itself

Abstract

Adolescents and young adults (AYAs) with cancer, defined by the National Cancer Institute as having been diagnosed between the ages of 15 and 39 years old, have not benefited from the same improvements in quality of outcomes and survival that have been seen for individuals diagnosed in childhood or as older adults. Although is leukemia composed of a diverse group of diagnoses, leukemia AYA survivors share unique vulnerabilities with other AYA diagnostic groups. They will spend the majority of their lives as survivors, with clear evidence of adverse medical conditions, health care requirements, and social and psychological needs that differ not only from their peers but also, from the needs of other cancer survivor populations. Furthermore, they share a developmental stage of life in which careers, finances, and family concerns are uniquely impacted by the cancer diagnosis and treatment. Leukemia in AYAs typically presents with higher-risk biologic features, and treatment requires multiagent chemotherapy, including alkylating agents, anthracyclines, high-dose steroids, frequently intrathecal chemotherapy, and sometimes, cranial radiation. Thus, AYAs have significant risks for long-term complications, subsequent malignancies, and accelerated development of usual age-related comorbid conditions, such as cardiovascular disease and dyslipidemias. AYAs require specialized health care monitoring, surveillance for late effects, and periodic evaluation of psychosocial, health behavior, and life goal outcomes.

Indexed as

AdolescentAdultAge FactorsCancer SurvivorsFemaleHumansLeukemiaMaleYoung Adult

Identifiers

PMID30504303
PMCPMC6245964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.