Evidence map›Paper›PMID 30504273›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex.

Seika Inoue, Kanehiro Hayashi, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Ken-Ichiro Kubo, Kazunori Nakajima

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Unique "Reversed" Migration of Neurons in the Developing Claustrum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  7. Article
  8. KIFC1 Regulates the Trajectory of Neuronal Migration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Molecular Mechanisms of Cadherin Function During Cortical Migration.Frontiers in cell and developmental biology · 2020
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Seika InoueDepartment of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan, and.
Kanehiro HayashiDepartment of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan, and.
Kyota FujitaDepartment of Neuropathology, Medical Research Institute, Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Kazuhiko TagawaDepartment of Neuropathology, Medical Research Institute, Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
Hitoshi OkazawaDepartment of Neuropathology, Medical Research Institute, Center for Brain Integration Research, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.ORCID 0000-0002-6127-5046
Ken-Ichiro KuboDepartment of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan, and.ORCID 0000-0003-4023-5069
Kazunori NakajimaDepartment of Anatomy, Keio University School of Medicine, Tokyo 160-8582, Japan, and kazunori@keio.jp.ORCID 0000-0003-1864-9425
Keio University · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The actin cytoskeleton is crucial for neuronal migration in the mammalian developing cerebral cortex. The adaptor protein Drebrin-like (Dbnl) plays important roles in reorganization of the actin cytoskeleton, dendrite formation, and endocytosis by interacting with F-actin, cobl, and dynamin. Although Dbnl is known to be expressed in the brain, the functions of this molecule during brain development are largely unknown. In this study, to examine the roles of Dbnl in the developing cerebral cortex, we conducted experiments using mice of both sexes with knockdown of Dbnl, effected by

Indexed as

AnimalsCadherinsCell MembraneCell MovementCerebral CortexFemaleGene Expression Regulation, DevelopmentalGene Knockdown TechniquesLateral VentriclesMaleMiceMice, Inbred ICRMicrofilament ProteinsNeuronsPregnancysrc Homology DomainsCadherinsDbnl protein, mouseMicrofilament Proteinscerebral cortexdevelopmentneuronal migrationphosphorylation

Identifiers

PMID30504273
PMCPMC6343645
OpenAlexW2903169740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.