Evidence map›Paper›PMID 30504268›Full record

ArticleThe EMBO journal2019

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca

Saverio Marchi, Mariangela Corricelli, Alessio Branchini, Veronica Angela Maria Vitto, Sonia Missiroli, Giampaolo Morciano, Mariasole Perrone, Mattia Ferrarese, Carlotta Giorgi, Mirko Pinotti and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effects of Adalimumab on Mitochondria of Psoriatic Mesenchymal Stem Cells.Journal of cellular and molecular medicine · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Calcium signaling in mitochondrial intermembrane space.Biochemical Society transactions · 2024
    Review
  10. Article
  11. CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  12. Article
  13. MICU1's calcium sensing beyond mitochondrial calcium uptake.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. AnPlant signaling & behavior · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 4 countries.

Saverio MarchiLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy saverio.marchi@unife.it paolo.pinton@unife.it.ORCID 0000-0003-2708-1843
Mariangela CorricelliLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Alessio BranchiniDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-6113-2694
Veronica Angela Maria VittoLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Sonia MissiroliLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Giampaolo MorcianoLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Mariasole PerroneLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Mattia FerrareseDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Carlotta GiorgiLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Mirko PinottiDepartment of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.
Lorenzo GalluzziDepartment of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0003-2257-8500
Guido KroemerUniversité Paris Descartes, Sorbonne Paris Cité, Paris, France.ORCID 0000-0002-9334-4405
Paolo PintonLaboratory for Technologies of Advanced Therapies (LTTA), Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy saverio.marchi@unife.it paolo.pinton@unife.it.ORCID 0000-0001-7108-6508
University of Ferrara · ITDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although mitochondria play a multifunctional role in cancer progression and Ca

Indexed as

AnimalsCalciumCalcium-Binding ProteinsCalcium SignalingCation Transport ProteinsHEK293 CellsHeLa CellsHumansMiceMitochondriaMitochondrial Membrane Transport ProteinsNeoplasmsNeoplasm TransplantationPhosphorylationProtein DomainsProto-Oncogene Proteins c-aktCalciumCalcium-Binding ProteinsCation Transport ProteinsMICU1 protein, humanMitochondrial Membrane Transport ProteinsProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAktcalciumcancerMICU1mitochondria

Identifiers

PMID30504268
PMCPMC6331721
OpenAlexW2903416169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.