Evidence map›Paper›PMID 30504124›Full record

ArticleDevelopment (Cambridge, England)2018

The polarity protein VANG-1 antagonizes Wnt signaling by facilitating Frizzled endocytosis.

Chun-Wei He, Chien-Po Liao, Chung-Kuan Chen, Jérôme Teulière, Chun-Hao Chen, Chun-Liang Pan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Chun-Wei HeInstitute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan.
Chien-Po LiaoInstitute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan.
Chung-Kuan ChenInstitute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan.ORCID 0000-0002-6973-2563
Jérôme TeulièreDepartment of Molecular Cell Biology, University of California, Berkeley, CA 94720-3204, USA.ORCID 0000-0002-0965-4399
Chun-Hao ChenInstitute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan.
Chun-Liang PanInstitute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan chunliangpan@ntu.edu.tw.ORCID 0000-0003-0108-3138
National Taiwan University · TWUniversity of California, Berkeley · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Signaling that instructs the migration of neurons needs to be tightly regulated to ensure precise positioning of neurons and subsequent wiring of the neuronal circuits. Wnt-Frizzled signaling controls neuronal migration in metazoans, in addition to many other aspects of neural development. We show that

Indexed as

Cell PolarityEndocytosisWnt Signaling PathwayAmino Acid SequenceAnimalsBase SequenceCaenorhabditis elegansCaenorhabditis elegans ProteinsCell MovementFrizzled ReceptorsLarvaMultiprotein ComplexesNeuronsPhosphoproteinsCaenorhabditis elegans ProteinsFrizzled ReceptorsMultiprotein ComplexesPhosphoproteinsVang-1 protein, C elegansC. elegansEndocytosisFrizzledNeuronal migrationPlanar polarityWnt signaling

Identifiers

PMID30504124
PMCPMC6919297
OpenAlexW2902862174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.