ArticleVirology2019
Differential suppression of persistent insect specific viruses in trans-infected wMel and wMelPop-CLA Aedes-derived mosquito lines.
Article in Virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Characterization of Culex pipiens cell lines: virus infection and RNAi response.Parasites & vectors · 2026Article
- Infections ofViruses · 2025Article
- The impact of temperature and insect-specific viruses on the transmission of alphaviruses byMicrobiology spectrum · 2025Article
- Aedes albopictus saliva contains a richer microbial community than the midgut.Parasites & vectors · 2024Article
- AntiviralmBio · 2024Article
- Article
- The interplay between vector microbial community and pathogen transmission on the invasive Asian tiger mosquito,Frontiers in microbiology · 2023Review
- Transient Introgression ofPathogens (Basel, Switzerland) · 2022Article
- Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus.Parasites & vectors · 2021Article
- Isolation in Natural Host Cell Lines ofInsects · 2021Article
- Growth and Maintenance ofInsects · 2021Review
- Uncovering the Worldwide Diversity and Evolution of the Virome of the MosquitoesMicroorganisms · 2021Article
- UsingJournal of virology · 2021Review
- Symbiotic Interactions Between Mosquitoes and Mosquito Viruses.Frontiers in cellular and infection microbiology · 2021Review
- A Novel Anphevirus inViruses · 2020Article
- Exploiting insect-specific viruses as a novel strategy to control vector-borne disease.Current opinion in insect science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Wolbachia suppresses the replication of +ssRNA viruses such as dengue and Zika viruses in Aedes aegypti mosquitoes. However, the range of viruses affected by this endosymbiont is yet to be explored. Recently, novel insect-specific viruses (ISVs) have been described from numerous mosquito species and mosquito-derived cell lines. Cell-fusing agent virus (Flaviviridae) and Phasi Charoen-like virus (Bunyaviridae) persistently infect the Ae. aegypti cell line Aag2 which has been used for experimental studies with both the wMel and wMelPop-CLA strains. Wolbachia was found to restrict the replication of CFAV but not the PCLV infection in these lines. Furthermore, an additional Ae. albopictus cell line (RML-12) which contained either wMel or wMelPop-CLA was assessed. While no infectious +ssRNA or dsRNA viruses were detected, a PCLV infection was identified. These observations provide additional evidence to support that insect-specific, +ssRNA viruses can be suppressed in cell culture by Wolbachia but -ssRNA viruses may not.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.