ReviewJournal of controlled release : official journal of the Controlled Release Society2019
Ultrasound-responsive droplets for therapy: A review.
Review in Journal of controlled release : official journal of the Controlled Release Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed.
- Phase change nanodroplets: Challenges and clinical potential.Acta pharmaceutica Sinica. B · 2026Review
- Perfluorocarbon nanodroplets are cytocompatible with osteoblast-lineage cells and modulate in vitro osteoclastogenesis differentially in normoxia and hypoxia.Scientific reports · 2026Article
- Thermally Activated Vaporization of Fluorocarbon-In-Hydrocarbon Exoskeletal Droplets.ACS omega · 2026Article
- Real-time drug release monitoring from acoustically responsive scaffolds.Ultrasonics sonochemistry · 2026Article
- Smart Ultrasound-Responsive Nanoparticles for Drug Delivery.IEEE nanotechnology magazine · 2026Article
- Radiation induced vaporization of exoskeletal droplets as potential x-ray acoustic contrast agents.Medical physics · 2025Article
- The Role of Acoustic Parameters in Droplet Vaporization of Perfluoropentane Nanodroplets forACS applied materials & interfaces · 2025Article
- Optimising the manufacture of perfluorocarbon nanodroplets through varying sonication parameters.Ultrasonics sonochemistry · 2025Article
- Optical and Acoustic Characterization of Phase-Shift Droplets with Varying Shell Compositions.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Microneedle technology for enhanced topical treatment of skin infections.Bioactive materials · 2025Review
- Twinkling Peptide Nanoemulsions Enable Precision Ultrasound Detection of Atherosclerotic Plaques.Advanced functional materials · 2025Article
- Ischemia/Reperfusion Injury Enhances Accumulation of Perfluoropropane Droplets.Ultrasound in medicine & biology · 2025Article
- Polydopamine Nanobowl-Armoured Perfluorocarbon Emulsions: Tracking Thermal- and Photothermal-Induced Phase Change through Neutron Scattering.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- MicroRNAs regulating apoptosis and delivery strategies for treating intervertebral disc degeneration.Frontiers in cell and developmental biology · 2025Review
- Ultrasound nanodroplets loaded with Siglec-G siRNA and FeJournal of nanobiotechnology · 2024Article
- Experimental & numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials.Journal of the mechanical behavior of biomedical materials · 2024Article
- Laser-activated perfluorocarbon nanodroplets for intracerebral delivery and imaging via blood-brain barrier opening and contrast-enhanced imaging.Journal of nanobiotechnology · 2024Article
- Programmable ultrasound imaging guided theranostic nanodroplet destruction for precision therapy of breast cancer.Ultrasonics sonochemistry · 2024Article
- Repeatable Acoustic Vaporization of Coated Perfluorocarbon Bubbles for Micro-Actuation Inspired byBiomimetics (Basel, Switzerland) · 2024Article
- Device for Multifocal Delivery of Ultrasound Into Deep Brain Regions in Humans.IEEE transactions on bio-medical engineering · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The last two decades have seen the development of acoustically activated droplets, also known as phase-change emulsions, from a diagnostic tool to a therapeutic agent. Through bubble effects and triggered drug release, these superheated agents have found potential applications from oncology to neuromodulation. The aim of this review is to summarise the key developments in therapeutic droplet design and use, to discuss the current challenges slowing clinical translation, and to highlight the new frontiers progressing towards clinical implementation. The literature is summarised by addressing the droplet design criteria and by carrying out a multiparametric study of a range of droplet formulations and their associated vaporisation thresholds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.