Evidence map›Paper›PMID 30503317›Full record

ArticleEnvironment international2019

Lead exposure during childhood and subsequent anthropometry through adolescence in girls.

Andrea L Deierlein, Susan L Teitelbaum, Gayle C Windham, Susan M Pinney, Maida P Galvez, Kathleen L Caldwell, Jeffery M Jarrett, Ryszard Gajek, Lawrence H Kushi, Frank Biro and 2 more

Abstract read
In one paragraph

Article in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Metal mixtures and adiposity indicators in women from Northern Mexico.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andrea L DeierleinDepartment of Epidemiology, College of Global Public Health, New York University, NY, NY, USA. Electronic address: ald8@nyu.edu.
Susan L TeitelbaumDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, NY, NY, USA.
Gayle C WindhamEnvironmental Health Investigations Branch, California Department of Public Health, Richmond, CA, USA.
Susan M PinneyUniversity of Cincinnati College of Medicine, Department of Environmental Health, Cincinnati, OH, USA.
Maida P GalvezDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, NY, NY, USA.
Kathleen L CaldwellNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jeffery M JarrettNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Ryszard GajekEnvironmental Health Investigations Branch, California Department of Public Health, Richmond, CA, USA.
Lawrence H KushiDivision of Research, Kaiser Permanente, Oakland, CA, USA.
Frank BiroDivision of Adolescent Medicine, Cincinnati Children's Hospital Center, Cincinnati, OH, USA.
Mary S WolffDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, NY, NY, USA.
Breast Cancer and Environment Research Program

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI PINNEY, SUSAN MENGEL · 1992 to 2022
$35.4M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
MOUNT SINAI INSTITUTES FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR029887 · NCRR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SAMPSON, HUGH A · 2009 to 2011
$19.2M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Bay Area Breast Cancer &the Environment Research CenterU01ES012801 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HIATT, ROBERT A · 2003 to 2010
$12.4M
Center for Environment and Mammary Gland DevelopmentU01ES012771 · NIEHS · FOX CHASE CANCER CENTER · PI RUSSO, JOSE · 2003 to 2009
$11.1M
Puberty &Cancer Initiation: Environment Diet &ObesityU01ES012770 · NIEHS · UNIVERSITY OF CINCINNATI · PI BORNSCHEIN, ROBERT L · 2003 to 2009
$9.0M
PRENATAL PCB EXPOSURE &NEURODEVELOPMENTAL OUTCOMES IN ADOLESCENCE &ADULTHOODP01ES009584 · NIEHS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI WOLFF, MARY S · 1999 to 2009
$7.3M
Environmental and Genetic Determinants of PubertyU01ES019454 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WOLFF, MARY S · 2010 to 2016
$5.8M
Environmental Epigenetics on PubertyU01ES019453 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI BIRO, FRANK M · 2010 to 2015
$5.4M
NCATS NIH HHS UL1 TR001425NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1 RR026314NCRR NIH HHS UL1 RR029887NIEHS NIH HHS P01 ES009584NIEHS NIH HHS P30 ES006096NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R00 ES023474NIEHS NIH HHS U01 ES012770NIEHS NIH HHS U01 ES012771NIEHS NIH HHS U01 ES012801NIEHS NIH HHS U01 ES019435NIEHS NIH HHS U01 ES019453NIEHS NIH HHS U01 ES019454NIEHS NIH HHS U01 ES019457
6 · The paper itself

Abstract

introductionCross-sectional studies suggest that postnatal blood lead (PbB) concentrations are negatively associated with child growth. Few studies prospectively examined this association in populations with lower PbB concentrations. We investigated longitudinal associations of childhood PbB concentrations and subsequent anthropometric measurements in a multi-ethnic cohort of girls.

methodsData were from The Breast Cancer and the Environment Research Program at three sites in the United States (U.S.): New York City, Cincinnati, and San Francisco Bay Area. Girls were enrolled at ages 6-8 years in 2004-2007. Girls with PbB concentrations collected at ≤10 years old (mean 7.8 years, standard deviation (SD) 0.82) and anthropometry collected at ≥3 follow-up visits were included (n = 683). The median PbB concentration was 0.99 μg/d (10th percentile = 0.59 μg/dL and 90th percentile = 2.00 μg/dL) and the geometric mean was 1.03 μg/dL (95% Confidence Interval (CI): 0.99, 1.06). For analyses, PbB concentrations were dichotomized as <1 μg/dL (n = 342) and ≥1 μg/dL (n = 341). Anthropometric measurements of height, body mass index (BMI), waist circumference (WC), and percent body fat (%BF) were collected at enrollment and follow-up visits through 2015. Linear mixed effects regression estimated how PbB concentrations related to changes in girls' measurements from ages 7-14 years.

resultsAt 7 years, mean difference in height was -2.0 cm (95% CI: -3.0, -1.0) for girls with ≥1 μg/dL versus <1 μg/dL PbB concentrations; differences persisted, but were attenuated, with age to -1.5 cm (95% CI: -2.5, -0.4) at 14 years. Mean differences for BMI, WC, and BF% at 7 years between girls with ≥1 μg/dL versus <1 μg/dL PbB concentrations were -0.7 kg/m

conclusionsThese findings suggest that higher concentrations of PbB during childhood, even though relatively low by screening standards, may be inversely associated with anthropometric measurements in girls.

Indexed as

Body Mass IndexEnvironmental ExposureWaist CircumferenceAdolescentChildCross-Sectional StudiesFemaleHumansLeadNew York CityLeadBody fatChildhoodGirlsHeightLead

Identifiers

PMID30503317
PMCPMC6366327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.