Evidence map›Paper›PMID 30502946›Full record

ArticleMethods in enzymology2018

Analysis of Bacterial Transcription by "Massively Systematic Transcript End Readout," MASTER.

Irina O Vvedenskaya, Seth R Goldman, Bryce E Nickels

Open access · greenAbstract read
In one paragraph

Article in Methods in enzymology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Promoter-sequence determinants and structural basis of primer-dependent transcription initiation inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Irina O VvedenskayaWaksman Institute and Department of Genetics, Rutgers University, Piscataway, NJ, United States.
Seth R GoldmanWaksman Institute and Department of Genetics, Rutgers University, Piscataway, NJ, United States.
Bryce E NickelsWaksman Institute and Department of Genetics, Rutgers University, Piscataway, NJ, United States. Electronic address: bnickels@waksman.rutgers.edu.
Rutgers, The State University of New Jersey · USAckerman Institute for the Family · US

Funding

Transcription: Mechanism and RegulationR35GM118059 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2016 to 2025
$7.1M
Systematic analysis of protein-nucleic acid interactions during transcriptionR01GM115910 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI NICKELS, BRYCE EDWARD · 2015 to 2015
$306k
NIGMS NIH HHS R01 GM115910NIGMS NIH HHS R35 GM118059
6 · The paper itself

Abstract

A systems-level view of cellular gene expression requires understanding the mechanistic principles governing each step of transcription. In this chapter, we describe a massively multiplexed method for the analysis of the relationship between nucleic acid sequence and transcription termed "MASTER," for massively systematic transcript end readout. MASTER enables parallel measurements of transcription output from at least 4

Indexed as

High-Throughput Nucleotide SequencingPromoter Regions, GeneticSequence Analysis, RNATranscription, GeneticTranscription Initiation SiteHigh-throughput sequencingNCINNoncanonical initiating nucleotidePromoterRNA cappingRNA polymeraseRNA-seqTranscriptionTranscription initiationTranscription start site selection

Identifiers

PMID30502946
PMCPMC6352903
OpenAlexW2897837901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.