Evidence map›Paper›PMID 30502862›Full record

ArticleTopics in companion animal medicine2018

Retrospective Biomolecular Investigation of Coxiella burnetii and Leptospira spp. DNA in Cases of Abortion, Stillbirth and Neonatal Mortality in Dogs and Cats.

Valentina Stefanetti, Agnese Compagnone, Chiara Sordini, Fabrizio Passamonti, Elisa Rampacci, Livia Moscati, Maria Luisa Marenzoni

Open access · greenAbstract read
In one paragraph

Article in Topics in companion animal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Coxiellosis in Dogs-A Hitherto Masked Zoonosis in India: An Insight From Seromolecular Investigation and Risk Factor Analysis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  2. Detection ofPathogens (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Pathogens (Basel, Switzerland) · 2022
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Valentina StefanettiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy. Electronic address: valentina.stefanetti@unipg.it.
Agnese CompagnoneDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Chiara SordiniDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Fabrizio PassamontiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Elisa RampacciDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Livia MoscatiIstituto Zooprofilattico Sperimentale of Umbria and Marche, Perugia, Italy.
Maria Luisa MarenzoniDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
University of Perugia · ITIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abortion and neonatal mortality are events that can occur in breeding bitches and queens. It has been reported that up to 55% and 33% of these cases remain without a known cause, respectively, in canine and feline pregnancies. Unusual abortigenic and potentially zoonotic agents, including Coxiella burnetii and Leptospira spp., may be involved in these cases. C. burnetii is able to cause reproductive disorders in cattle, sheep and goats, and cases of abortion have been observed in dogs and cats. Moreover, several outbreaks of C. burnetii infection in humans have been caused by delivering bitches and queens, and some of these animals experienced abortion. Leptospira interrogans sensu lato is able to cause abortion or stillbirth in several animal species and its abortigenic role has occasionally been described in bitches and queens. The aim of this study was to search for C. burnetii and Leptospira spp. DNA in a retrospective series of 103 cases of canine and feline abortion, stillbirth, and neonatal mortality submitted for the identification of possible infectious agents. One hundred and fifty-one specimens were tested using PCR assays and found negative for C. burnetii and Leptospira DNA. However, in 49 samples (47.6%) other infectious causes of abortion, stillbirth, and neonatal mortality were identified. These results showed that C. burnetii and Leptospira spp. are probably not common abortigenic agents or causes of neonatal deaths in dogs. However, given the potential abortigentic and zoonotic role of these agents, surveillance of canine and feline abortion, stillbirth, and neonatal mortality could be advisable for a systematic investigation of these events.

Indexed as

Abortion, VeterinaryAnimalsAnimals, NewbornCat DiseasesCatsCoxiella burnetiiDNA, BacterialDog DiseasesDogsFemaleLeptospiraPolymerase Chain ReactionPregnancyPregnancy Complications, InfectiousRetrospective StudiesStillbirthDNA, BacterialCoxiella burnetii Leptospira sppdog cat abortion neonatal mortality PCR

Identifiers

PMID30502862
PMCPMC7104966
OpenAlexW2888768906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.