Evidence map›Paper›PMID 30502778›Full record

Trial reportValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2018

Cost-Effectiveness of a Comprehensive Approach for Hypertension Control in Low-Income Settings in Argentina: Trial-Based Analysis of the Hypertension Control Program in Argentina.

Federico Augustovski, Martín Chaparro, Alfredo Palacios, Lizheng Shi, Andrea Beratarrechea, Vilma Irazola, Adolfo Rubinstein, Katherine Mills, Jiang He, Andrés Pichon Riviere

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. Framework for developing cost-effectiveness analysis threshold: the case of Egypt.The Journal of the Egyptian Public Health Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Federico AugustovskiInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina; School of Public Health, University of Buenos Aires, Buenos Aires, Argentina. Electronic address: faugustovski@iecs.org.ar.
Martín ChaparroInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina.
Alfredo PalaciosInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina.
Lizheng ShiDepartment of Global Health Management and Policy, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Andrea BeratarrecheaInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina.
Vilma IrazolaInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina.
Adolfo RubinsteinInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina; School of Public Health, University of Buenos Aires, Buenos Aires, Argentina.
Katherine MillsDepartment of Epidemiology and Tulane University Translational Science Institute, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Jiang HeDepartment of Epidemiology and Tulane University Translational Science Institute, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Andrés Pichon RiviereInstitute for Clinical Effectiveness and Health Policy (IECS/CONICET), Buenos Aires, Argentina; School of Public Health, University of Buenos Aires, Buenos Aires, Argentina.

Funding

Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI JING CHEN · 2016 to 2026
$25.3M
Comprehensive Approach for Hypertension Prevention and Control in ArgentinaU01HL114197 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI HE, JIANG · 2012 to 2016
$2.0M
NHLBI NIH HHS U01 HL114197NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

backgroundA recent cluster randomized trial evaluating a multicomponent intervention showed significant reductions in blood pressure in low-income hypertensive subjects in Argentina.

objectivesTo assess the cost-effectiveness of this intervention.

methodsA total of 1432 hypertensive participants were recruited from 18 primary health care centers. The intervention included home visits led by community health workers, physician education, and text messaging. Resource use and quality of life data using the three-level EuroQol five-dimensional questionnaire were prospectively collected. The study perspective was that of the public health care system, and the time horizon was 18 months. Intention-to-treat analysis was used to analyze cost and health outcomes (systolic blood pressure [SBP] change and quality-adjusted life-years [QALYs]). A 1 time gross domestic product per capita per QALY was used as the cost-effectiveness threshold (US $14,062).

resultsBaseline characteristics were similar in the two arms. QALYs significantly increased by 0.06 (95% confidence interval [CI] 0.04-0.09) in the intervention group, and SBP net difference favored the intervention group: 5.3 mm Hg (95% CI 0.27-10.34). Mean total costs per participant were higher in the intervention arm: US $304 in the intervention group and US $154 in the control group (adjusted difference of US $140.18; 95% CI US $75.41-US $204.94). The incremental cost-effectiveness ratio was $3299 per QALY (95% credible interval 1635-6099) and US $26 per mm Hg of SBP (95% credible interval 13-46). Subgroup analysis showed that the intervention was cost-effective in all prespecified subgroups (age, sex, cardiovascular risk, and body mass index).

conclusionsThe multicomponent intervention was cost-effective for blood pressure control among low-income hypertensive patients.

Indexed as

Blood PressureCost-Benefit AnalysisPovertyAdultAgedArgentinaCommunity Health WorkersFemaleHealth Care CostsHealth PromotionHealth ResourcesHome Care ServicesHumansHypertensionMaleMiddle Agedcost-effectivenesshypertensionlow-income settingprimary care

Identifiers

PMID30502778
PMCPMC6457112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.