Evidence map›Paper›PMID 30502097›Full record

ArticleSocial science & medicine (1982)2021

Affective response to physical activity as an intermediate phenotype.

Harold H Lee, Jessica A Emerson, Lauren Connell Bohlen, David M Williams

Open access · greenAbstract read
In one paragraph

Article in Social science & medicine (1982), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 43 citations in OpenAlex.

  1. Modeling longitudinal variation in affective response to exercise across a 16-week randomized control trial (RCT).Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
    Trial
  2. Article
  3. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Harold H LeeDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA. Electronic address: harold_lee@brown.edu.
Jessica A EmersonDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Lauren Connell BohlenDepartment of Kinesiology, University of Rhode Island, Kingston, RI, USA.
David M WilliamsDepartment of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Brown University · USUniversity of Rhode Island · US

Funding

Training in Behavioral & Preventive MedicineT32HL076134 · NHLBI · MIRIAM HOSPITAL · PI John Graham Thomas · 2006 to 2026
$5.7M
When Outcomes Matter: A Temporal Analysis of Instrumental and Affective Outcomes of Exercise Behavior using Ecological Momentary AssessmentF31CA206245 · NCI · BROWN UNIVERSITY · PI EMERSON, JESSICA A. · 2016 to 2017
$88k
Genetic effects of BDNF on physical activity adherence: Affective response to physical activity as a phenotypic mediatorF31HL140817 · NHLBI · BROWN UNIVERSITY · PI LEE, HAROLD H. · 2018 to 2019
$45k
NCI NIH HHS F31 CA206245NHLBI NIH HHS F31 HL140817NHLBI NIH HHS T32 HL076134
6 · The paper itself

Abstract

Over the past seventy years, biomedical and epidemiological research has shown that regular physical activity (PA) is critical for physical and mental health. Despite this knowledge, physical inactivity is the fourth leading risk factor for global mortality, accounting for 9% (5.3 million) of premature deaths annually. We suggest this mismatch between knowing about the risks of PA and engaging in regular PA can be reconciled by focusing less on expected health benefits of PA and more on how people feel during PA. Specifically, in this position paper, we argue that affective response (feeling good versus bad) to PA is an intermediate phenotype that can explain significant variance in PA behavior and is, in turn, a function of genetic variability. In making this argument, we first review empirical evidence showing that affective response to PA predicts future physical activity behavior. Second, we systematically review research on single nucleotide morphisms (SNPs) that are associated with affective response to PA. Investigating affective response to PA as an intermediate phenotype will allow future researchers to move beyond asking "What SNPs are associated with PA?", and begin asking "How do these SNPs influence PA?", thus ultimately optimizing the translation of knowledge gained from genomic data to intervention development.

Indexed as

ExerciseSedentary BehaviorHumansMotor ActivityPhenotypeRisk FactorsAffectExerciseIntermediate phenotypeMechanismMotivationPhysical activity

Identifiers

PMID30502097
PMCPMC6510653
OpenAlexW2899619769

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.