Evidence map›Paper›PMID 30501987›Full record

Observational studyHPB : the official journal of the International Hepato Pancreato Biliary Association2019

Can post-hoc video review of robotic pancreaticoduodenectomy predict portal/superior mesenteric vein margin status in pancreatic adenocarcinoma?

Jae P Jung, Mazen S Zenati, Ahmad Hamad, Melissa E Hogg, Richard L Simmons, Amer H Zureikat, Herbert J Zeh, Brian A Boone

Open access · bronzeAbstract readObservational StudyVideo-Audio Media
In one paragraph

Observational study in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Employing Advanced Technology to Reduce Postoperative Pancreatic Fistula.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jae P JungDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Mazen S ZenatiDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Ahmad HamadDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Melissa E HoggDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Richard L SimmonsDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Amer H ZureikatDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA.
Herbert J ZehDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA; Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Office E.7102B, Dallas, TX 75390, USA.
Brian A BooneDepartment of Surgery, University of Pittsburgh Medical Center, 5150 Center Ave, Pittsburgh, PA 15232, USA; Department of Surgery, West Virginia University, PO Box 9238 HSCS, Morgantown, WV 26506, USA. Electronic address: brian.boone@hsc.wvu.edu.
University of Pittsburgh Medical Center · USWest Virginia University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

backgroundAchieving margin negative resection is a significant determinant of outcome in pancreatic adenocarcinoma (PDA). However, because of the fibrotic nature of PDA, it can be difficult to discriminate fibrosis from active disease intra-operatively. We sought to determine if post-hoc video review of robotic pancreatico-duodenectomy (RPD) could predict the portal/superior mesenteric vein (PV/SMV) margin status on final pathology.

methodsExperienced pancreatic surgeons, blinded to patient and operative variables, reviewed the PV/SMV margin for available RPD videos of consecutive PDA patients from 9/2012 through 6/2017.

results107 RPD videos were reviewed. Of 76 patients (71%) predicted to have a negative vein margin on video review, 20 patients (26%) had a pathologic positive margin. 25 of 31 patients (81%) predicted to have positive margin on video review were positive on pathology. The specificity of video prediction was 90.3% with a sensitivity of 55.6% and an accuracy of 75.7%.

conclusionPost-hoc video review prediction is unable to reliably predict a positive (R1) margin at the portal vein/SMV, suggesting that intra-operative clinical assessment may be suboptimal in determining the need for more extensive resections.

Indexed as

AgedCarcinoma, Pancreatic DuctalFemaleFollow-Up StudiesHumansMaleMargins of ExcisionMesenteric VeinsMiddle AgedNeoplasm InvasivenessPancreatic NeoplasmsPancreaticoduodenectomyPortal VeinRetrospective StudiesRobotic Surgical ProceduresVascular Neoplasms

Identifiers

PMID30501987
PMCPMC6631331
OpenAlexW2903462103

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.