Evidence map›Paper›PMID 30501557›Full record

ArticleNanomedicine (London, England)2018

Development of photoactive Sweet-C

Maciej Serda, Matthew J Ware, Jared M Newton, Sanchit Sachdeva, Martyna Krzykawska-Serda, Lam Nguyen, Justin Law, Andrew O Anderson, Steven A Curley, Lon J Wilson and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nanomedicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Putting a "CPharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. ACS biomaterials science & engineering · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Evaluation of the Biodistribution of Serinolamide-Derivatized CNanomaterials (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Maciej SerdaDepartment of Chemistry & Smalley-Curl Institute, Rice University, Houston, TX 77251, USA.
Matthew J WareMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Jared M NewtonMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Sanchit SachdevaMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Martyna Krzykawska-SerdaMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Lam NguyenMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Justin LawMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Andrew O AndersonMichael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Steven A CurleyDepartment of Chemistry & Smalley-Curl Institute, Rice University, Houston, TX 77251, USA.
Lon J WilsonDepartment of Chemistry & Smalley-Curl Institute, Rice University, Houston, TX 77251, USA.
Stuart J CorrDepartment of Chemistry & Smalley-Curl Institute, Rice University, Houston, TX 77251, USA.
Baylor College of Medicine · USRice University · USUniversity of Silesia in Katowice · PL

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI RICE, ANDREW P · 1994 to 2015
$21.7M
TRANS-NETWORK PROJECTSU54CA143837 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FERRARI, MAURO · 2009 to 2014
$10.8M
Training Program in Translational Biology and Molecular MedicineT32GM088129 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI ROONEY, CLIONA M., VAN DEN VEYVER, IGNATIA B · 2010 to 2019
$3.0M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
Immunomodulatory Nanoparticles in Combination with Immune Checkpoint Inhibitors for the Systemic Treatment of Immunosuppressive HPV Associated Oropharyngeal CancerF31DE026682 · NIDCR · BAYLOR COLLEGE OF MEDICINE · PI NEWTON, JARED MICHAEL · 2016 to 2019
$118k
NCI NIH HHS P30 CA125123NCI NIH HHS U54 CA143837NCRR NIH HHS S10 RR024574NIAID NIH HHS P30 AI036211NIDCR NIH HHS F31 DE026682NIGMS NIH HHS T32 GM088129NIH HHS P30AI036211NIH HHS P30CA125123NIH HHS S10RR024574
6 · The paper itself

Abstract

aimGlycoconjugated C MATERIALS &

methodsHerein, we describe the synthesis and biological characterization of a hexakis-glucosamine C

resultsSynthesized fullerene derivative predominantly accumulates in the nucleus of pancreatic stellate cells; is inherently nontoxic up to concentrations of 1 mg/ml; and is photoactive when illuminated with blue and green light, allowing its use as a photodynamic therapy agent.

conclusionObtained glycoconjugated nanoplatform is a promising nanotherapeutic for pancreatic cancer.

Indexed as

AdenocarcinomaAntibodiesAntineoplastic AgentsCell- and Tissue-Based TherapyCell Line, TumorCell NucleusCell SurvivalFullerenesGlycoconjugatesHumansPancreatic NeoplasmsPancreatic Stellate CellsPhotochemotherapyPhotosensitizing AgentsAntibodiesAntineoplastic AgentsFullerenesGlycoconjugatesPhotosensitizing Agents[60]fullerenefullerene antibodyglycoconjugatespancreatic stellate cellsphotodynamic therapy

Identifiers

PMID30501557
PMCPMC6462851
OpenAlexW2903518111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.