Evidence map›Paper›PMID 30501201›Full record

ArticleJournal of proteome research2019

TomahaqCompanion: A Tool for the Creation and Analysis of Isobaric Label Based Multiplexed Targeted Assays.

Christopher M Rose, Brian K Erickson, Devin K Schweppe, Rosa Viner, Jae Choi, John Rogers, Ryan Bomgarden, Steven P Gygi, Donald S Kirkpatrick

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Immunoproteomics: The Evolution from Classical Methods to Emerging Techniques.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  3. Targeted Analyses of MHC-I Peptides Using TOMAHAQ.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Enhanced Sample Multiplexing-Based Targeted Proteomics with Intelligent Data Acquisition.Journal of the American Society for Mass Spectrometry · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Sample multiplexing for targeted pathway proteomics in aging mice.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Christopher M RoseDepartment of Microchemistry, Proteomics and Lipidomics , Genentech , South San Francisco , California 94080 , United States.ORCID 0000-0002-7502-3368
Brian K EricksonDepartment of Cell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.ORCID 0000-0002-1150-5042
Devin K SchweppeDepartment of Cell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.ORCID 0000-0002-3241-6276
Rosa VinerThermo Fisher Scientific , San Jose , California 95134 , United States.
Jae ChoiThermo Fisher Scientific , Rockford , Illinois 61101 , United States.
John RogersThermo Fisher Scientific , Rockford , Illinois 61101 , United States.
Ryan BomgardenThermo Fisher Scientific , Rockford , Illinois 61101 , United States.
Steven P GygiDepartment of Cell Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Donald S KirkpatrickDepartment of Microchemistry, Proteomics and Lipidomics , Genentech , South San Francisco , California 94080 , United States.
Thermo Fisher Scientific (United States) · USHarvard University · US

Funding

New Sample Multiplexing Technologies to Identify Chemical Probes and Illuminate Ubiquitin BiologyR01GM067945 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GYGI, STEVEN P · 2003 to 2024
$10.5M
NIGMS NIH HHS R01 GM067945
6 · The paper itself

Abstract

Triggered by Offset, Multiplexed, Accurate mass, High resolution, and Absolute Quantitation (TOMAHAQ) is a recently introduced targeted proteomics method that combines peptide and sample multiplexing. TOMAHAQ assays enable sensitive and accurate multiplexed quantification by implementing an intricate data collection scheme that comprises multiple MS

Indexed as

HumansPeptidesProteomicsSoftwareStaining and LabelingTandem Mass SpectrometryTime FactorsUser-Computer InterfaceYeastsPeptidescomputational analysisisobaric labelingmass spectrometryopen sourceOrbitrapquantitative proteomicsSPS-MS3targeted proteomicsTMTTOMAHAQ

Identifiers

PMID30501201
PMCPMC7315617
OpenAlexW2903146800

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.