Evidence map›Paper›PMID 30501053›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents.

Ahmet Çağrı Karaburun, Ulviye Acar Çevik, Derya Osmaniye, Begüm Nurpelin Sağlık, Betül Kaya Çavuşoğlu, Serkan Levent, Yusuf Özkay, Ali Savaş Koparal, Mustafa Behçet, Zafer Asım Kaplancıklı

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 53 citations in OpenAlex.

  1. Antimicrobial Activity of 1,3,4-Thiadiazole Derivatives.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Design, Synthesis, and Evaluation of Novel 2Molecules (Basel, Switzerland) · 2022
    Article
  10. In Vitro Anti-Molecules (Basel, Switzerland) · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ahmet Çağrı KaraburunDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. ackarabu@anadolu.edu.tr.
Ulviye Acar ÇevikDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. uacar@anadolu.edu.tr.
Derya OsmaniyeDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. dosmaniye@anadolu.edu.tr.
Begüm Nurpelin SağlıkDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. bnsaglik@anadolu.edu.tr.
Betül Kaya ÇavuşoğluDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. betulkaya@anadolu.edu.tr.
Serkan LeventDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. serkanlevent@anadolu.edu.tr.ORCID 0000-0003-3692-163X
Yusuf ÖzkayDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. yozkay@anadolu.edu.tr.
Ali Savaş KoparalOpen Education Faculty, Anadolu University, Eskişehir 26470, Turkey. askopara@anadolu.edu.tr.
Mustafa BehçetDepartment of Medical Microbiology, Faculty of Medicine, Abant İzzet Baysal University, Bolu 14280, Turkey. mustafabehcet@ibu.edu.tr.
Zafer Asım KaplancıklıDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey. zakaplan@anadolu.edu.tr.ORCID 0000-0003-2252-0923
Anadolu University · TRBolu Abant İzzet Baysal University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (

Indexed as

Antifungal AgentsCandidaErgosterolMicrobial Sensitivity TestsMolecular Docking SimulationThiadiazoles1,3,4-thiadiazoleAntifungal AgentsErgosterolThiadiazoles1,3,4-thiadiazole14-α-sterol demethylaseADMEantifungaldockingthione-thiol tautomerism

Identifiers

PMID30501053
PMCPMC6321371
OpenAlexW2903192328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.