Evidence map›Paper›PMID 30500988›Full record

ArticleJournal of the American Geriatrics Society2019

Early Post-Intensive Care Syndrome among Older Adult Sepsis Survivors Receiving Home Care.

Barbara Riegel, Liming Huang, Mark E Mikkelsen, Ann Kutney-Lee, Alexandra L Hanlon, Christopher M Murtaugh, Kathryn H Bowles

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. What Animal Models Can Tell Us About Long-Term Psychiatric Symptoms in Sepsis Survivors: a Systematic Review.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Pooled it
  2. Measuring health-related quality of life in sepsis survivors and caregivers: a mapping review and a preliminary conceptual framework.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Review
  3. Article
  4. Observational
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Post-intensive Care Syndrome.Annals of geriatric medicine and research · 2021
    Article
  13. Observational
  14. Psychological and neuropsychiatric implications of COVID-19.European archives of psychiatry and clinical neuroscience · 2021
    Review
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Barbara RiegelSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-0970-136X
Liming HuangSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Mark E MikkelsenPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ann Kutney-LeeSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Alexandra L HanlonSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Christopher M MurtaughVisiting Nurse Service of New York, New York, New York.
Kathryn H BowlesSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · USVNS Health · USPhiladelphia VA Medical Center · US

Funding

Sepsis Survivors' Post-Acute Outcomes: Impact of Early Home Health and MD VisitsR01NR016014 · NINR · VISITING NURSE SERVICE OF NEW YORK · PI BOWLES, KATHRYN HELENE · 2015 to 2025
$4.6M
NINR NIH HHS R01 NR016014
6 · The paper itself

Abstract

BACKGROUND/

objectivesNew or worsened disabilities in functional, cognitive, or mental health following an intensive care unit (ICU) stay are referred to as post-intensive care syndrome (PICS). PICS has not been described in older adults receiving home care. Our aim was to examine the relationship between length of ICU stay and PICS among older adults receiving home care. We expected that patients in the ICU for 3 days or longer would demonstrate significantly more disability in all three domains on follow-up than those not in the ICU. A secondary aim was to identify patient characteristics increasing the odds of disability.

designRetrospective cohort study.

settingHospitalization for sepsis in the United States.

participantsA total of 21 520 Medicare patients receiving home care and reassessed a median of 1 day (interquartile range 1-2 d) after hospital discharge. MEASUREMENTS: PICS was defined as a decline or worsening in one or more of 16 indicators tested before and after hospitalization using OASIS (Home Health Outcome and Assessment Information Set) and Medicare claims data.

resultsThe sample was predominantly female and white. All had sepsis, and most (81.8%) had severe sepsis. In adjusted models, an ICU stay of 3 days or longer, compared with no ICU stay, increased the odds of physical disability. Overall, the declines were modest and found in specific activities of daily living (16% for feeding and lower body dressing to 26% for oral medicine management). No changes were identified in cognition or mental health. Significant determinants of new or worsened physical disabilities were sepsis severity, older age, depression, frailty, and dementia.

conclusionOlder adults receiving home care who develop sepsis and are in an ICU for 3 days or longer are likely to develop new or worsened physical disabilities. Whether these disabilities remain after the early postdischarge phase requires further study. J Am Geriatr Soc 67:520-526, 2019.

Indexed as

Activities of Daily LivingAftercareDisability EvaluationPhysical Functional PerformanceSepsisAgedCognitionCritical CareFemaleGeriatric AssessmentHome Care ServicesHumansIntensive Care UnitsLength of StayMaleOutcome and Process Assessment, Health Careactivities of daily livingcognitive dysfunctioncritical carehome care servicesmental healthpost-intensive care syndromesepsis

Identifiers

PMID30500988
PMCPMC6402981
OpenAlexW2902363503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.