ReviewPain medicine (Malden, Mass.)2019
Perioperative Management of Buprenorphine: Solving the Conundrum.
Review in Pain medicine (Malden, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Perioperative pain management interventions in opioid user patients: an overview of reviews.BMC anesthesiology · 2024Pooled it
- Management of opioid use disorder and associated conditions among hospitalized adults: A Consensus Statement from the Society of Hospital Medicine.Journal of hospital medicine · 2022Pooled it
- Opioid-induced analgesia among persons with opioid use disorder receiving methadone or buprenorphine: A systematic review of experimental pain studies.Drug and alcohol dependence · 2021Pooled it
- An Individualized, Interdisciplinary Approach to the Perioperative Care of Patients on Buprenorphine.Current pain and headache reports · 2026Review
- Geographic differences in buprenorphine and methadone prescribing for surgical patients with opioid use disorder.Drug and alcohol dependence reports · 2026Article
- Perioperative Management of Patients on Buprenorphine.Current pain and headache reports · 2026Review
- Managing Acute Surgical Pain in Patients on Buprenorphine: A Case-Based Learning Module.Orthopedic reviews · 2026Article
- Buvidal/Brixadi - a long-acting injectable buprenorphine formulation for the treatment of opioid dependence.Pain management · 2025Review
- Mini-review: Perioperative pain management in gynecologic oncology - strategies and future directions.Gynecologic oncology reports · 2025Review
- Narrative review: Managing buprenorphine and opioid use disorder in the perioperative setting.Pain practice : the official journal of World Institute of Pain · 2025Review
- The Effect of Lidocaine Splash Block Followed by Suspensory Ligament Massage in Female Dogs Undergoing Ovariohysterectomy: A Prospective Study.Animals : an open access journal from MDPI · 2024Article
- Methadone and Buprenorphine in the Perioperative Setting: A Review of the Literature.Current pain and headache reports · 2024Review
- The Efficacy of Buprenorphine in Preoperative and Postoperative Patients: A Literature Review.Cureus · 2024Review
- How Do I Manage Acute Pain for Patients Prescribed Buprenorphine for Opioid Use Disorder?NEJM evidence · 2024Review
- A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder.Drugs in R&D · 2023Review
- Buprenorphine Continuation During Critical Illness Associated With Decreased Inpatient Opioid Use in Individuals Maintained on Buprenorphine for Opioid Use Disorder in a Retrospective Study.Journal of clinical pharmacology · 2023Article
- Multidisciplinary Management of Opioid Use-Related Infective Endocarditis: Treatment, QTc Values, and Cardiac Arrests due to Ventricular Fibrillation.Journal of clinical medicine · 2023Article
- Pain Management After Cesarean Delivery Among Women with Opioid Use Disorder: Results from a Retrospective Pregnancy Cohort in a Rural Region of the Midwest.Women's health reports (New Rochelle, N.Y.) · 2023Article
- Procedural moderate sedation in patients with opioid addiction and chronic pain: a practical primer for the radiologist.Abdominal radiology (New York) · 2022Review
- Patients on Buprenorphine Formulations Undergoing Surgery.Current pain and headache reports · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThere is no consensus on the optimal perioperative management of patients on buprenorphine (BUP) for opioid use disorder (OUD). This article will review the available literature on BUP and the analgesic efficacy of BUP combined with full mu-opioid agonists and discuss the conflicting management strategies in the context of acute pain and our institution's protocol for the periprocedural management of BUP.
methodsWe searched published data on BUP periprocedural management from inception through March 2018 without language restrictions. Study selection included publications reporting outcomes on perioperative pain management in OUD patients maintained on BUP.
resultsOur search resulted in four case reports supporting periprocedural discontinuation of BUP and two case series, one secondary observational study, one prospective matched cohort study, and four retrospective cohort studies supporting periprocedural continuation of BUP. No clinical trials were identified.
conclusionsMaintaining BUP perioperatively does not lead to worsened clinical outcomes. Patients can receive adequate pain control from mu-opioid agonists while maintained on BUP. Based upon available evidence, we recommend continuing BUP at a reduced dose when indicated to avoid withdrawal symptoms and to facilitate the analgesic efficacy of mu-opioid agonists administered in combination for acute postoperative pain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.