Evidence map›Paper›PMID 30500432›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2019

Applications of FLIKA, a Python-based image processing and analysis platform, for studying local events of cellular calcium signaling.

Kyle L Ellefsen, Jeffrey T Lock, Brett Settle, Carley A Karsten, Ian Parker

Abstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Guidelines for evaluating endothelial function in vascular tissue.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Dissociation of inositol 1,4,5-trisphosphate from IPThe Journal of biological chemistry · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Termination of CaCell calcium · 2021
    Article
  10. Article
  11. Article
  12. ER-luminal [CaeLife · 2020
    Article
  13. IPeLife · 2020
    Article
  14. Article
  15. Spatial-temporal patterning of CaSeminars in cell & developmental biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyle L EllefsenDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, USA.
Jeffrey T LockDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, USA. Electronic address: lockj@uci.edu.
Brett SettleDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, USA.
Carley A KarstenDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, USA.
Ian ParkerDepartment of Neurobiology & Behavior, UC Irvine, Irvine, CA, USA; Department of Physiology & Biophysics, UC Irvine, Irvine, CA, USA.

Funding

Elementary Events of Intracellular Calcium SignalingR37GM048071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PARKER, IAN · 2011 to 2020
$5.3M
Spatial Dynamics of Cellular Calcium SignalingF31GM119330 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ELLEFSEN, KYLE L · 2016 to 2017
$68k
NIGMS NIH HHS F31 GM119330NIGMS NIH HHS R37 GM048071
6 · The paper itself

Abstract

The patterning of cytosolic Ca

Indexed as

Calcium SignalingImage Processing, Computer-AssistedProgramming LanguagesHEK293 CellsHumansMicroscopy, FluorescenceCa(2+) puffsCa(2+) signalingImage analysisIP(3) receptors

Identifiers

PMID30500432
PMCPMC6461507

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.