Evidence map›Paper›PMID 30499652›Full record

ArticleACS applied materials & interfaces2018

Switchable Photoacoustic Imaging of Glutathione Using MnO

Chang Liu, Depeng Wang, Ye Zhan, Lingyue Yan, Qian Lu, Michael Yu Zarng Chang, Jingwen Luo, Lidai Wang, Dan Du, Yuehe Lin and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  13. Chemodynamic nanomaterials for cancer theranostics.Journal of nanobiotechnology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Chang LiuDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Depeng WangDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Ye ZhanDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Lingyue YanDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Qian LuSchool of Mechanical and Materials Engineering , Washington State University , Pullman , Washington 99164 , United States.
Michael Yu Zarng ChangDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Jingwen LuoDepartment of Mechanical and Biomedical Engineering , City University of Hong Kong , Hong Kong , P. R. China.
Lidai WangDepartment of Mechanical and Biomedical Engineering , City University of Hong Kong , Hong Kong , P. R. China.
Dan DuSchool of Mechanical and Materials Engineering , Washington State University , Pullman , Washington 99164 , United States.ORCID http://orcid.org/0000-0003-1952-4042
Yuehe LinSchool of Mechanical and Materials Engineering , Washington State University , Pullman , Washington 99164 , United States.ORCID http://orcid.org/0000-0003-3791-7587
Jun XiaDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.
Yun WuDepartment of Biomedical Engineering , University at Buffalo, The State University of New York , Buffalo , New York 14260 , United States.ORCID http://orcid.org/0000-0002-6926-777X
University at Buffalo, State University of New York · USWashington State University · USCity University of Hong Kong · HK

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
NCATS NIH HHS UL1 TR001412
6 · The paper itself

Abstract

Glutathione is overexpressed in tumor cells and regulates cancer growth, metastasis, and drug resistance. Therefore, detecting glutathione levels may greatly facilitate cancer diagnosis and treatment response monitoring. Photoacoustic (PA) imaging is a noninvasive modality for high-sensitivity, high-resolution, deep-tissue optical imaging. Switchable PA probes that offer signal on/off responses to tumor targets would further improve the detection sensitivity and signal-to-noise ratio of PA imaging. Here, we explore the use of MnO

Indexed as

Manganese CompoundsMelanomaNeoplasms, ExperimentalOxidesSkin NeoplasmsAnimalsCell Line, TumorGlutathioneHumansMiceNanotubesOptical ImagingPhotoacoustic TechniquesGlutathioneManganese Compoundsmanganese oxideOxidescancerglutathionemelanomaMnO2nanotubesphotoacoustic imagingswitchable contrast reagent

Identifiers

PMID30499652
PMCPMC13094744
OpenAlexW2902452211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.