ArticleBJU international2019
Examining the relationship between complications and perioperative mortality following radical cystectomy: a population-based analysis.
Article in BJU international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Advances in the management of localized bladder cancers.Nature reviews. Clinical oncology · 2026Review
- Article
- Clinical utility of a novel perioperative quality assessment metric, trifecta, for radical cystectomy.International journal of clinical oncology · 2025Article
- Previous maximal transurethral resection of bladder tumor lead to unfavorable perioperative outcomes following radical cystectomy.International urology and nephrology · 2025Article
- Temporal patterns of major postoperative events after radical cystectomy: analysis of 90-day morbidity.World journal of urology · 2025Article
- Article
- Complications and oncologic outcome in bladder cancer patients receiving radical cystectomy after intravesical instillation treatment.PloS one · 2025Article
- The feasibility and safety of robotic-assisted salvage radical cystectomy.BJUI compass · 2025Article
- Radical cystectomy in patients aged < 80 years versus ≥ 80 years: analysis of preoperative geriatric assessment scores in predicting postoperative morbidity and mortality.World journal of urology · 2024Article
- Article
- Impact of Medicaid Expansion on Abdominal Surgery Morbidity, Mortality, and Hospital Readmission.The Journal of surgical research · 2023Article
- Emerging Roles of Circulating Tumor DNA for Increased Precision and Personalization in Radiation Oncology.Seminars in radiation oncology · 2023Review
- Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: A cohort study.PLoS medicine · 2021Article
- Impact of inflammatory bowel disease on radical prostatectomy outcomes and costs of care.Prostate international · 2021Article
- Major Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes.European urology open science · 2021Article
- Intensified and Standardized Digital Communication with Cystectomy Patients as a Potentially Simple and Effective Modality for Early Detection of Postoperative Complications: Results from a Pilot Study.European urology open science · 2020Article
- Association between perioperative morbidity and mortality after radical cystectomy: an opportunity to understand the complication snowball effect.Translational andrology and urology · 2019Article
- Perioperative mortality following radical cystectomy: the slippery slope of complications.Translational andrology and urology · 2019Article
- Experience of surgeon, hospital, and comprehensive cancer team critical to the outcomes of radical cystectomy and urinary diversion.Translational andrology and urology · 2019Article
- The clinical and economic burden of perioperative complications of radical cystectomy.Translational andrology and urology · 2019Article
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the incidence of perioperative complications after radical cystectomy (RC) and assess their impact on 90-day postoperative mortality during the index stay and upon readmission. PATIENTS AND
methodsA total of 57 553 patients with bladder cancer (unweighted cohort: 9137 patients) treated with RC, at 360 hospitals in the USA between 2005 and 2013 within the Premier Healthcare Database, were used for analysis. The 90-day perioperative mortality was the primary outcome. Multivariable regression was used to predict the probability of mortality; models were adjusted for patient, hospital, and surgical characteristics.
resultsAn increase in the number of complications resulted in an increasing predicted probability of mortality, with a precipitous increase if patients had four or more complications compared to one complication during hospitalisation following RC (index stay; 1.0-9.7%, P < 0.001) and during readmission (2.0-13.1%, P < 0.001). A readmission complication nearly doubled the predicted probability of postoperative mortality as compared to an initial complication (3.9% vs 7.4%, P < 0.001). During the initial hospitalisation cardiac- (odds ratio [OR] 3.1, 95% confidence interval [CI] 1.9-5.1), pulmonary- (OR 4.8, 95% CI 2.8-8.4), and renal-related (OR 3.6, 95% CI 2-6.7) complications had the most significant impact on the odds of mortality across categories examined.
conclusionsThe number and nature of complications have a distinct impact on mortality after RC. As complications increase there is an associated increase in perioperative mortality.
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