Evidence map›Paper›PMID 30499383›Full record

ArticleRadiation research2019

Continuous One Year Oral Administration of the Radiation Mitigator, MMS350, after Total-Body Irradiation, Restores Bone Marrow Stromal Cell Proliferative Capacity and Reduces Senescence in Fanconi Anemia (Fanca

Aranee Sivananthan, Donna Shields, Renee Fisher, Wen Hou, Xichen Zhang, Darcy Franicola, Michael W Epperly, Peter Wipf, Joel S Greenberger

Open access · greenAbstract read
In one paragraph

Article in Radiation research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Combined injury: irradiation with skin or bone wounds in rodent models.Journal of radiological protection : official journal of the Society for Radiological Protection · 2021
    Article
  4. Article
  5. Article
  6. Targets for protection and mitigation of radiation injury.Cellular and molecular life sciences : CMLS · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Aranee Sivananthana Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Donna Shieldsa Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Renee Fishera Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Wen Houa Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Xichen Zhanga Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Darcy Franicolaa Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Michael W Epperlya Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
Peter Wipfb Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Joel S Greenbergera Department of Radiation Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania 15213.
UPMC Hillman Cancer Center · USUniversity of Pittsburgh · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
Training and EducationU19AI068021 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENBERGER, JOEL S · 2005 to 2019
$44.4M
TRADITIONAL AND FLUOROUS SYNTHESIS APPROACHES TO DICTYOSTATIN ANTICANCER AGENTSP01CA078039 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAZO, JOHN S. · 1998 to 2009
$9.9M
NCI NIH HHS P01 CA078039NCI NIH HHS P30 CA047904NIAID NIH HHS U19 AI068021
6 · The paper itself

Abstract

We quantitated age-related accumulation of senescent cells in irradiated Fanconi anemia (FA) (Fanca

Indexed as

Whole-Body IrradiationAdministration, OralAnimalsCell ProliferationCellular SenescenceEthers, CyclicFanconi AnemiaFanconi Anemia Complementation Group A ProteinFemaleMaleMesenchymal Stem CellsMiceMice, KnockoutRadiation-Protective AgentsSulfoxidesTumor MicroenvironmentEthers, CyclicFanca protein, mouseFanconi Anemia Complementation Group A ProteinMMS350Radiation-Protective AgentsSulfoxides

Identifiers

PMID30499383
PMCPMC6388094
OpenAlexW2902328476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.