Evidence map›Paper›PMID 30499382›Full record

ArticleGlobal health action2018

Time to anti-retroviral therapy among people living with HIV enrolled into care in Myanmar: how prepared are we for 'test and treat'?

Kyaw Zin Linn, Hemant Deepak Shewade, Kyaw Ko Ko Htet, Thae Maung Maung, San Hone, Htun Nyunt Oo

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Article in Global health action, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyaw Zin Linna National AIDS Programme, Department of Public Health , Ministry of Health and Sports , Nay Pyi Taw , Myanmar.
Hemant Deepak Shewadeb International Union Against Tuberculosis and Lung Disease (The Union) , South-East Asia Office , New Delhi , India.ORCID 0000-0002-8242-1911
Kyaw Ko Ko Htetd Department of Medical Research , Pyin Oo Lwin branch , Pyin Oo Lwin , Myanmar.
Thae Maung Maunge Department of Medical Research , Yangon Head Quarter , Myanmar.ORCID 0000-0002-1265-3813
San Honea National AIDS Programme, Department of Public Health , Ministry of Health and Sports , Nay Pyi Taw , Myanmar.
Htun Nyunt Ooa National AIDS Programme, Department of Public Health , Ministry of Health and Sports , Nay Pyi Taw , Myanmar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmong people living with HIV (PLHIV) enrolled into care, time to anti-retroviral therapy (ART) has not been studied in Myanmar. To inform progress, we conducted this operational research among treatment-naive PLHIV (≥18 years) enrolled during a period of three years (2014-2016) at Pyin Oo Lwin, Myanmar.

objectivesTo determine (i) the time from HIV diagnosis to ART initiation (time to ART) and associated factors and (ii) the association between time to ART and attrition (loss to follow-up and death) from ART care.

methodsThis was a retrospective cohort study involving a record review of secondary programme data. The PLHIV were followed up to 5 December 2017 for ART initiation and up to 31 March 2018 (date of censoring) for attrition during ART.

resultsOf 543 enrolled, 373 (69%) were found to be eligible and initiated on ART. Of 373, 245 (67%) were initiated within 6 weeks of enrolment. The median enrolment delay (from diagnosis) was 4 (IQR: 1, 14) days and median ART initiation delay (from ART eligibility) was 20 (IQR: 13, 36) days. The median time to ART (excluding the time interval in pre-ART care) was 29 (IQR: 18, 55) days and was significantly long in those with prevalent TB and CD4 count ≥ 500/mm

conclusionThe programme appears to be on track to initiate ART as soon as possible in a 'test and treat' scenario (implemented since September 2017) subject to interventions to reduce ART initiation delay.

Indexed as

AdultAnti-Retroviral AgentsCohort StudiesFemaleHIVHIV InfectionsHumansMaleMyanmarRetrospective StudiesTime FactorsAnti-Retroviral AgentsART initiationattritionHIV care cascadeoperational researchSORT ITtime to ART

Identifiers

PMID30499382
PMCPMC6282424

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.