Evidence map›Paper›PMID 30499222›Full record

ReviewMolecular oncology2019

Interplay between small and long non-coding RNAs in cutaneous melanoma: a complex jigsaw puzzle with missing pieces.

Mattia Riefolo, Elisa Porcellini, Emi Dika, Elisabetta Broseghini, Manuela Ferracin

Open access · goldAbstract readReview
In one paragraph

Review in Molecular oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Review
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  11. Article
  12. Review
  13. High expression of lncRNAOncology letters · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma.Medical oncology (Northwood, London, England) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mattia RiefoloDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.
Elisa PorcelliniDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.
Emi DikaDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.
Elisabetta BroseghiniDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.
Manuela FerracinDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Italy.
University of Bologna · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG 18464Fondazione Pallotti (University of Bologna)
6 · The paper itself

Abstract

The incidence of cutaneous melanoma (CM) has increased in the past few decades. The biology of melanoma is characterized by a complex interaction between genetic, environmental and phenotypic factors. A greater understanding of the molecular mechanisms that promote melanoma cell growth and dissemination is crucial to improve diagnosis, prognostication, and treatment of CM. Both small and long non-coding RNAs (lncRNAs) have been identified to play a role in melanoma biology; microRNA and lncRNA expression is altered in transformed melanocytes and this in turn has functional effects on cell proliferation, apoptosis, invasion, metastasis, and immune response. Moreover, specific dysregulated ncRNAs were shown to have a diagnostic or prognostic role in melanoma and to drive the establishment of drug resistance. Here, we review the current literature on small and lncRNAs with a role in melanoma, with the aim of putting into some order this complex jigsaw puzzle.

Indexed as

ApoptosisBiomarkers, TumorCell CycleCell ProliferationCutaneous Malignant MelanomaGene Expression Regulation, NeoplasticHumansMelanomaMicroRNAsPrognosisRNA, Long NoncodingSkin NeoplasmsTumor EscapeBiomarkers, TumorMicroRNAsRNA, Long Noncodingcutaneous melanomamicroRNAnon-coding RNA

Identifiers

PMID30499222
PMCPMC6322194
OpenAlexW2902412269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.