Evidence map›Paper›PMID 30499177›Full record

ArticleJournal of clinical laboratory analysis2019

Efficacy of different hemodialysis methods on dendritic cell marker CD40 and CD80 and platelet activation marker CD62P and P10 in patients with chronic renal failure.

Xin-Fang Wang, Bei-Hao Zhang, Xiao-Qing Lu, Pei Wang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xin-Fang WangDepartment of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Bei-Hao ZhangDepartment of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiao-Qing LuDepartment of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Pei WangDepartment of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID http://orcid.org/0000-0002-1018-9308
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic renal failure (CRF) has become a major public health concern, which increases the risk of stroke and systemic thromboembolism. Therefore, therapeutic strategies are in urgent requirement. This study was conducted for investigating efficacy of hemodialysis (HD), hemodiafiltration (HDF), and hemoperfusion (HP) in patients with CRF and the correlation with the presence of complications following HD therapy.

methodsThe therapeutic effect, living quality, biochemical indicators, and dry weight were detected before and after the treatment regimens. Flow cytometry was conducted to detect expressions of dendritic cell markers (CD40 and CD80) and platelet activation markers (CD62P and P10), and the relationship between their expression and therapeutic effect as well as the association of these expressions with complications was analyzed.

resultsAfter HD therapy, patients presented with decreased serum creatinine, serum phosphorus, triglyceride, parathyroid hormone, and β

conclusionThe aforementioned results indicated that CRF patients treated with HP exhibited higher expression of CD40 and CD80 and lower expression of CD62P and P10, suggesting that HP is conferred to have better efficacy than HDF and HD. Therefore, HP may be a promising clinical regimen for treatment of CRF patients.

Indexed as

Kidney Failure, ChronicRenal DialysisAdultAgedB7-1 AntigenBiomarkersCD40 AntigensDendritic CellsFemaleHumansMaleMiddle AgedPlatelet ActivationP-SelectinB7-1 AntigenBiomarkersCD40 AntigensP-SelectinSELP protein, humanCD40CD62PCD80chronic renal failurehemodialysis

Identifiers

PMID30499177
PMCPMC6818601
OpenAlexW2902489709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.