ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020
Analytical quantification of aortic valve 18F-sodium fluoride PET uptake.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
- Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis: A Double-Blind Randomized Controlled Trial.Circulation · 2021Trial
- Imaging small dynamic lesions using positron emission tomography and computed tomography: anEuropean heart journal. Imaging methods and practice · 2025Article
- Latent Coronary Plaque Morphology From Computed Tomography Angiography, Molecular Disease Activity on Positron Emission Tomography, and Clinical Outcomes.Arteriosclerosis, thrombosis, and vascular biology · 2023Article
- Serum lipoprotein(a) and bioprosthetic aortic valve degeneration.European heart journal. Cardiovascular Imaging · 2023Article
- The Role of Positron Emission Tomography in Advancing the Understanding of the Pathogenesis of Heart and Vascular Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Advanced Cardiac Imaging in the Assessment of Aortic Stenosis.Journal of cardiovascular development and disease · 2023Review
- Advances in the Assessment of Coronary Artery Disease Activity with PET/CT and CTA.Tomography (Ann Arbor, Mich.) · 2023Review
- Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography.Medical physics · 2022Article
- Artificial intelligence-based quantification of cardiac 18F-sodium fluoride uptake.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Quantifying sodium [EJNMMI research · 2022Article
- Bypass Grafting and Native Coronary Artery Disease Activity.JACC. Cardiovascular imaging · 2022Article
- Aortic valve imaging usingEJNMMI physics · 2022Article
- Lipoprotein(a) has no major impact on calcification activity in patients with mild to moderate aortic valve stenosis.Heart (British Cardiac Society) · 2022Article
- Machine Learning withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Native Aortic Valve Disease Progression and Bioprosthetic Valve Degeneration in Patients With Transcatheter Aortic Valve Implantation.Circulation · 2021Article
- CardiovascularJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Clinical implications ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Detecting native and bioprosthetic aortic valve disease usingJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Review
- Advances in Quantitative Analysis ofMolecular imaging · 2021Review
- Whole-vessel coronaryEuropean journal of nuclear medicine and molecular imaging · 2020Article
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundChallenges to cardiac PET-CT include patient motion, prolonged image acquisition and a reduction of counts due to gating. We compared two analytical tools, FusionQuant and OsiriX, for quantification of gated cardiac 18F-sodium fluoride (18F-fluoride) PET-CT imaging.
methodsTwenty-seven patients with aortic stenosis were included, 15 of whom underwent repeated imaging 4 weeks apart. Agreement between analytical tools and scan-rescan reproducibility was determined using the Bland-Altman method and Lin's concordance correlation coefficients (CCC).
resultsImage analysis was faster with FusionQuant [median time (IQR) 7:10 (6:40-8:20) minutes] compared with OsiriX [8:30 (8:00-10:10) minutes, p = .002]. Agreement of uptake measurements between programs was excellent, CCC = 0.972 (95% CI 0.949-0.995) for mean tissue-to-background ratio (TBR
conclusion18F-fluoride PET quantification with FusionQuant and OsiriX is comparable. FusionQuant with motion correction offers advantages with respect to analysis time and reproducibility of TBR
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.