ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
Clinical significance of weight changes at diagnosis in solid tumours.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Article
- Exploring the optimal indicator of short-term peridiagnosis weight dynamics to predict cancer survival: A multicentre cohort study.Journal of cachexia, sarcopenia and muscle · 2024Article
- Prospective Cohort Study of Pre- and Postdiagnosis Obesity and Endometrial Cancer Survival.Journal of the National Cancer Institute · 2022Article
- Association of body mass index with toxicity and survival in pediatric patients treated with cisplatin-containing regimens.Pediatric hematology and oncology · 2021Article
- Stability of Symptom Clusters in Patients With Gastrointestinal Cancers Receiving Chemotherapy.Journal of pain and symptom management · 2019Article
- Role that anorexia and weight loss play in patients with stage IV lung cancer.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaObservational
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWeight changes occur throughout the cancer trajectory. Most research has focused on changes during or after treatment, so clinical significance of change at diagnosis remains unclear. This study aimed to determine prevalence, predictors and prognostic significance of weight changes at diagnosis in outpatients with solid tumours presenting to a tertiary academic medical centre.
methodsA retrospective study of the electronic medical record was conducted (n = 6477). Those with weight recorded within 6 months of cancer diagnosis (pre-diagnosis, T
resultsMean age is 61 ± 12.5 years. Common tumour sites: breast (17%; n = 725), prostate (16%; n = 664), lung (14%; n = 599). 15% (n = 652) had metastatic disease at T
conclusionsMost had evidence of clinically significant weight changes at diagnosis. Weight loss at diagnosis was associated with a higher risk of further weight loss. A detailed weight history at cancer diagnosis is essential to identify and intervene for those most at risk of weight change-related early mortality.
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