Evidence map›Paper›PMID 30498847›Full record

ArticleClinical neuroradiology2019

Predictors of Good Outcome After Endovascular Treatment for Patients with Vertebrobasilar Artery Occlusion due to Intracranial Atherosclerotic Stenosis.

Xuelei Zhang, Gang Luo, Dapeng Mo, Ning Ma, Feng Gao, Jingyu Zhang, Zhongrong Miao

Abstract read
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In one paragraph

Article in Clinical neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xuelei ZhangDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Gang LuoDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Dapeng MoDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ning MaDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Feng GaoDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jingyu ZhangDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhongrong MiaoDepartment of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. zhongrongm@163.com.
Beijing Tian Tan Hospital · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the predictors for good outcome of endovascular therapy (EVT) for patients with acute vertebrobasilar artery occlusion (VBAO) due to intracranial atherosclerosis stenosis (ICAS).

methodsFrom April 2012 to February 2018, patients with VBAO due to ICAS who received EVT were retrospectively analyzed. ICAS was defined as fixed stenosis of >70%, or a degree of fixed stenosis >50% in addition to either perfusion impairment or evidence to re-occlusion. Good outcome was defined as mRS≤2 at 90 days. Both logistic regression and receiver operating characteristic curve (ROC) analyses were performed to explore the predictors.

resultsAmong 103 patients enrolled in the analysis, 40.8% achieved good outcome. Prior antiplatelet therapy (OR, 7.301; 95% CI, 1.761-30.265; P=0.006), EVT+IVT (OR, 7.343; 95% CI, 1.621-33.263; P=0.010 ), the pc-ASPECT on DWI (OR, 1.705; 95% CI, 1.127-2.580; P=0.012), BATMAN (OR, 1.395; 95% CI, 1.005-1.937; P=0047), general anesthesia (OR, 0.081; 95% CI, 0.010-0.633; P=0.017), onset-to-recanalization time (≤542min vs. >542min) (OR, 0.194; 95% CI, 0.057-0.661; P=0.009) and the initial NIHSS (OR, 0.882; 95% CI, 0.820-0.949; P=0.001) were significantly associated with good outcome in logistic regression. Based on ROC analyses, initial NIHSS score (area under the curve [AUC]= 0.816, p <0.001; cutoff,19.5; sensitivity, 78.7%; specificity, 72.5%) was significant predictors of good outcome.

conclusionsFor patients with VBAO due to ICAS, prior antiplatelet therapy, EVT+IVT, local anesthesia, short onset-to-recanalization time, a low initial NIHSS, a high pc-ASPECT and BATMAN might be helpful to predict the good outcome at 90 days after EVT.

Indexed as

AgedArterial Occlusive DiseasesCombined Modality TherapyEndovascular ProceduresFemaleHumansIntracranial ArteriosclerosisMaleMiddle AgedPlatelet Aggregation InhibitorsPrognosisRetrospective StudiesROC CurveThrombolytic TherapyTreatment OutcomeVertebrobasilar InsufficiencyPlatelet Aggregation InhibitorsAcute ischemic strokeAntiplatelet therapyBATMANPc-ASPECTThrombectomy

Identifiers

PMID30498847
OpenAlexW2903164936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.