ArticleBMJ paediatrics open2018
Extubation from high-frequency oscillatory ventilation in extremely low birth weight infants: a prospective observational study.
Article in BMJ paediatrics open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Peri-extubation settings in preterm neonates: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2024Pooled it
- [Safety of two ventilator weaning strategies after high-frequency oscillatory ventilation in preterm infants with respiratory distress syndrome: a prospective randomized controlled trial].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Trial
- Nomogram-based prediction model for extubation failure in preterm infants with invasive mechanical ventilation.Italian journal of pediatrics · 2025Article
- Respiratory Management of the Preterm Infant: Supporting Evidence-Based Practice at the Bedside.Children (Basel, Switzerland) · 2023Review
- Can Fraction of Inspired Oxygen Predict Extubation Failure in Preterm Infants?Children (Basel, Switzerland) · 2022Article
- [Research advances in the methods for weaning from high-frequency oscillatory ventilation in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019Review
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate if weaning from high-frequency oscillatory ventilation (HFOV) directly to a non-invasive mode of respiratory support is feasible and results in successful extubation in extremely low birth weight (ELBW) infants.
designProspective observational study.
settingTertiary neonatal intensive care unit. PATIENTS: One hundred and eight ELBW infants of 26.2±1.4 weeks of gestational age (GA) directly extubated from HFOV.
interventionsAll infants were managed with elective HFOV and received surfactant after a recruitment HFOV manoeuvre. Extubation was attempted at mean airways pressure (MAP) ≤6 cm H
main outcome measuresExtubation failure (clinical deterioration requiring reintubation) was defined as shorter than 7 days.
resultsNinety patients (83%) were successfully extubated and 18 (17%) required reintubation. No significant differences were found between the two groups in terms of birth weight, day of life and weight at the time of extubation. Multivariable analysis showed that GA (OR 1.71; 95% CI 1.04, 2.08) and higher MAP prior to surfactant (OR 1.51; 95% CI 1.06, 2.15) were associated with successful extubation.
conclusionsIn ELBW infants, direct extubation from HFOV at MAP ≤6 cm H
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