Evidence map›Paper›PMID 30498770›Full record

ArticleTransplantation direct2018

Development of a Predictive Model for Hyperglycemia in Nondiabetic Recipients After Liver Transplantation.

Henry Zelada, Lisa B VanWagner, Teresa Pollack, Devan Higginbotham, Lihui Zhao, Amy Yang, Mark E Molitch, Amisha Wallia

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. 2020 Clinical Update in Liver Transplantation.Journal of cardiothoracic and vascular anesthesia · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Henry ZeladaDivision of Endocrinology Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Lisa B VanWagnerDivision of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine., Chicago, IL.
Teresa PollackDivision of Endocrinology Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Devan HigginbothamNorthwestern Transplant Outcomes Research Collaborative (NUTORC)., Chicago, IL.
Lihui ZhaoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine.
Amy YangDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine.
Mark E MolitchDivision of Endocrinology Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Amisha WalliaDivision of Endocrinology Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Northwestern University · USNorthwestern Medicine · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
Implementation science to improve cardiovascular outcomes among liver transplant recipientsK23HL136891 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI VANWAGNER, LISA B · 2017 to 2020
$757k
Optimal Older Donor and Recipient Matching to Enhance Liver Transplant OutcomesR21AG049385 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SKARO, ANTON I, ZHAO, LIHUI · 2015 to 2016
$441k
NCATS NIH HHS KL2 TR001424NHLBI NIH HHS K23 HL136891NIA NIH HHS R21 AG049385
6 · The paper itself

Abstract

backgroundPosttransplant hyperglycemia has been associated with increased risks of transplant rejection, infections, length of stay, and mortality.

methodsTo establish a predictive model to identify nondiabetic recipients at risk for developing postliver transplant (LT) hyperglycemia, we performed this secondary, retrospective data analysis of a single-center, prospective, randomized, controlled trial of glycemic control among 107 adult LT recipients in the inpatient period. Hyperglycemia was defined as a posttransplant glucose level greater than 200 mg/dL after initial discharge up to 1 month following surgery. Candidate variables with

resultsForty-three (40.2%) patients had at least 1 episode of hyperglycemia after transplant after the resolution of the initial postoperative hyperglycemia. Variables selected for inclusion in the model (using model optimization strategies) included length of hospital stay (odds ratio [OR], 0.83;

conclusionsShorter hospital stay, use of glucose-lowering medications at discharge, donor female sex and donor white race are important determinants in predicting hyperglycemia in nondiabetic recipients after hospital discharge up to 1 month after liver transplantation.

Identifiers

PMID30498770
PMCPMC6233666
OpenAlexW2894649531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.