Evidence map›Paper›PMID 30498766›Full record

ArticleTransplantation direct2018

Renal Function, Albuminuria, and the Risk of Cardiovascular Events After Kidney Transplantation.

Ngan N Lam, Scott Klarenbach, Robert R Quinn, Brenda Hemmelgarn, Marcello Tonelli, Feng Ye, Pietro Ravani, Aminu K Bello, Daniel C Brennan, Krista L Lentine

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Ngan N LamDivision of Nephrology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Scott KlarenbachDivision of Nephrology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Robert R QuinnDivision of Nephrology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Brenda HemmelgarnDivision of Nephrology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Marcello TonelliDivision of Nephrology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Feng YeDivision of Nephrology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Pietro RavaniDivision of Nephrology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada.
Aminu K BelloDivision of Nephrology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Daniel C BrennanCenter for Transplantation, Johns Hopkins School of Medicine, Baltimore, MD.
Krista L LentineCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO.
University of Alberta · CAUniversity of Calgary · CASaint Louis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk of mortality and graft loss is higher in kidney transplant recipients with reduced estimated glomerular filtration rate (eGFR) and albuminuria. It is unclear whether these markers are also associated with cardiovascular events.

methodsWe examined linked healthcare databases in Alberta, Canada to identify kidney transplant recipients between 2002 and 2013 who had at least 1 outpatient serum creatinine and albuminuria measurement at 1-year posttransplant. We determined the relationship between categories of eGFR and albuminuria and the risk of subsequent cardiovascular events.

resultsAmong 1069 eligible kidney transplant recipients, the median age was 52 years, 37% were female, and 52% had eGFR ≥60 mL/min per 1.73 m

conclusionsThese findings suggest that eGFR and albuminuria should be used together to determine the risk of cardiovascular outcomes in transplant recipients.

Identifiers

PMID30498766
PMCPMC6233669
OpenAlexW2891880521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.