Evidence map›Paper›PMID 30498534›Full record

ArticleBeilstein journal of organic chemistry2018

Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors.

Rebeka Jójárt, Szabolcs Pécsy, György Keglevich, Mihály Szécsi, Réka Rigó, Csilla Özvegy-Laczka, Gábor Kecskeméti, Erzsébet Mernyák

Open access · diamondAbstract read
In one paragraph

Article in Beilstein journal of organic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Site-selective arylations of nature-inspired flavonoids or steroidal phenolsJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  3. Article
  4. Microwave-assisted Phospha-Michael addition reactions in the 13α-oestrone series andJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  5. Synthesis and evaluation of anticancer activities of 2- or 4-substituted 3-(Journal of enzyme inhibition and medicinal chemistry · 2021
    Article
  6. Transition metal-catalysed A-ring C-H activations and C(spJournal of enzyme inhibition and medicinal chemistry · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rebeka JójártDepartment of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Szabolcs PécsyDepartment of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
György KeglevichDepartment of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1521 Budapest, Hungary.ORCID 0000-0002-5366-472X
Mihály Szécsi1st Department of Medicine, University of Szeged, Korányi fasor 8-10, H-6720 Szeged, Hungary.
Réka RigóMembrane protein research group, Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary.
Csilla Özvegy-LaczkaMembrane protein research group, Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary.
Gábor KecskemétiDepartment of Medicinal Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.ORCID 0000-0002-5584-6869
Erzsébet MernyákDepartment of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
University of Szeged · HUInstitute of Molecular Life Sciences · HUBudapest University of Technology and Economics · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel 2- or 4-phosphonated 13α-estrone derivatives were synthesized via the Hirao reaction. Bromo regioisomers (2- or 4-) of 13α-estrone and its 3-benzyl or 3-methyl ether were reacted with diethyl phosphite or diphenylphosphine oxide using Pd(PPh

Indexed as

13α-estrone17β-HSD1 inhibitioncatalysisenzymeHirao reactionOATP2B1STS

Identifiers

PMID30498534
PMCPMC6244214
OpenAlexW2901310110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.