Evidence map›Paper›PMID 30498521›Full record

ArticleDiabetology & metabolic syndrome2018

Insulin Injection Technique Questionnaire: results of an international study comparing Brazil, Latin America and World data.

Luis Eduardo Calliari, Laura Cudizio, Balduino Tschiedel, Hermelinda C Pedrosa, Rosangela Rea, Augusto Pimazoni-Netto, Laurence Hirsch, Kenneth Strauss

Abstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Pen Needle Reuse in People with Diabetes Who Inject Insulin: A Narrative Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis Eduardo Calliari1Pediatric Endocrine Unit, Department of Pediatrics, Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, SP Brazil.
Laura Cudizio2Pediatric Endocrine Unit, Department of Pediatrics, Santa Casa de Sao Paulo, Sao Paulo, SP Brazil.
Balduino TschiedelInstitute of Children with Diabetes, Porto Alegre, RS Brazil.
Hermelinda C PedrosaEndocrinology Unit and Research Center-FEPECS, Taguatinga Regional Hospital, Secretariat of Health, Brasília, DF Brazil.
Rosangela Rea5Diabetes Unit, Endocrinology and Metabolism Service, Federal University of Parana, Curitiba, PR Brazil.
Augusto Pimazoni-Netto6Diabetes, Education and Control Group, Kidney Hospital, Federal University of Sao Paulo, Sao Paulo, SP Brazil.
Laurence HirschVP Medical Affairs, BD Diabetes Care, Franklin Lakes, NJ USA.
Kenneth StraussBD Diabetes Care, Erembodegem, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2014-2015, the largest international survey of insulin injection technique in patients with diabetes taking insulin was conducted in 42 countries, totaling 13,289 participants. In Brazil, patients from five public health centers were included. This study aims to evaluate insulin injection technique in Brazilian patients and compare results with Latin America (LatAm) and World data.

methodsThe insulin Injection Technique Questionnaire (ITQ) survey consisted of an initial patient section (questions applied by an experienced nurse), followed by observation of injection technique and examination of the injection sites by the health care professional.

resultsIn Brazil, 255 patients were evaluated: 25% had type 1 diabetes mellitus (T1DM) and 75% had T2DM. In this study, 79% of patients injected less than 4 times a day, and 17.3% used insulin pens, compared to 28% in LatAm and 86% worldwide. Syringes were used by 78% of patients in Brazil, compared to 65% in LatAm and 10% globally. Differences in needle length were substantial-nearly 64% in Brazil inject with 8 mm length needle compared to 48% in LatAm and 27% worldwide. Additionally, 48% of patients in Brazil skip doses, 80% reuse pen needles and 57% reuse syringes with 27% having lipohypertrophy by exam.

conclusionBrazilian patients use syringes more and pens less, inject with larger needles and have more lipohypertrophy when compared to Latin America and World data. Their re-use of needles and syringes is also high. This study showed that in Brazil, teaching of proper injection technique has to be more widespread, and more intensive during diabetes educational sessions, and the type of delivered supplies must be updated to smaller, shorter needles preferred by patients, in order to facilitate adherence to treatment. From the ITQ, we conclude that there are many aspects of insulin injection technique that may be improved in Brazil.

Indexed as

Diabetes mellitusInjections-subcutaneousInsulinNeedlesSyringesTechniques

Identifiers

PMID30498521
PMCPMC6258451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.