ArticleThe journal of venomous animals and toxins including tropical diseases2018
Purification and enzymatic characterization of a novel metalloprotease from
Article in The journal of venomous animals and toxins including tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Mechanisms and research progress of insect-derived medicines in intervention for ischemic stroke.IBRO neuroscience reports · 2025Review
- Toxicity Mechanism of Dangerous Scorpion Stings in Iran.Journal of arthropod-borne diseases · 2023Review
- P-I metalloproteinases and L-amino acid oxidases fromThe journal of venomous animals and toxins including tropical diseases · 2021Article
- Action of Varespladib (LY-315920), a Phospholipase AFrontiers in pharmacology · 2021Article
- A brief review on the natural history, venomics and the medical importance of bushmaster (Toxicon: X · 2020Article
- Scorpion Venom: Detriments and Benefits.Biomedicines · 2020Review
- Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundMETHODS AND
resultsLmr-MP was purified through two chromatographic steps and submitted to enzymatic characterization. It showed proteolytic activity on azocasein with maximum activity at pH 7.0-9.0. It was inhibited by EDTA (a metal chelator that removes zinc, which is essential for enzymatic activity) and no effect was observed with PMSF, iodoacetic acid or pepstatin (inhibitors of serine, cysteine and aspartyl proteases, respectively). Ca
conclusionThe purification procedure achieved a novel pure highly active metalloprotease from LmrV. This new molecule can help to understand the metalloproteases mechanisms of action, the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.