Evidence map›Paper›PMID 30498461›Full record

ArticleFrontiers in psychiatry2018

Evaluation of the Association Between Genetic Variants in Circadian Rhythm Genes and Posttraumatic Stress Symptoms Identifies a Potential Functional Allele in the Transcription Factor

Sarah D Linnstaedt, Yue Pan, Matthew C Mauck, Jenyth Sullivan, Christine Y Zhou, Lindsey Jung, Cathleen A Rueckeis, Jameson D Blount, Matthew S Carson, Andrew S Tungate and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Observational
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 1 country.

Sarah D LinnstaedtInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Yue PanInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Matthew C MauckInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Jenyth SullivanInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Christine Y ZhouInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Lindsey JungInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Cathleen A RueckeisInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Jameson D BlountInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Matthew S CarsonInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Andrew S TungateInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
Michael C KurzDepartment of Emergency Medicine, University of Alabama School of Medicine, Birmingham, AL, United States.
Phyllis L HendryDepartment of Emergency Medicine, University of Florida College of Medicine, Jacksonville, FL, United States.
Christopher LewandowskiDepartment of Emergency Medicine, Henry Ford Hospital, Detroit, MI, United States.
Teresa D'AnzaAlbuquerque Sexual Assault Nurse Examiner Collaborative, Albuquerque, NM, United States.
Elizabeth DatnerDepartment of Emergency Medicine, Albert Einstein Medical Center, Philadelphia, PA, United States.
Kathy BellForensic Nursing Program, Tulsa Police Department, Tulsa, OK, United States.
Megan LechnerForensic Nursing Program, Memorial Health System, Colorado Springs, CO, United States.
Jeffrey W ShuppDepartment of Surgery, The Burn Center, MedStar Washington Hospital Center, Georgetown University School of Medicine, Washington, DC, United States.
Bruce A CairnsJaycee Burn Center, University of North Carolina, Chapel Hill, NC, United States.
Samuel A McLeanInstitute for Trauma Recovery, University of North Carolina, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · USEinstein Medical Center Philadelphia · USHenry Ford Hospital · USMedStar Washington Hospital Center · USMemorial Health System · USRadiology Associates of Albuquerque · USUniversity of Alabama at Birmingham · USUniversity of Florida · US

Funding

Applying Biopsychosocial Model to Post-MVC Pain Development in African AmericansR01AR060852 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCLEAN, SAMUEL A. · 2011 to 2015
$3.6M
Influence of PTSD Symptoms on Chronic Pain Development after Sexual AssaultR01AR064700 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCLEAN, SAMUEL A. · 2014 to 2018
$3.6M
Key Molecular Mechanisms of Chronic Pain Vulnerability in Women Experiencing MVCK01AR071504 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LINNSTAEDT, SARAH · 2018 to 2021
$502k
NIAMS NIH HHS K01 AR071504NIAMS NIH HHS R01 AR060852NIAMS NIH HHS R01 AR064700
6 · The paper itself

Abstract

Previous studies suggest that genetic variants within genes affecting the circadian rhythm influence the development of posttraumatic stress symptoms (PTSS). In the present study, we used data from three emergency care-based cohorts to search genetic variants in circadian pathway genes previously associated with neuropsychiatric disorders for variants that influence PTSS severity. The three cohorts used included a discovery cohort of African American men and women enrolled following motor vehicle collision (

Indexed as

circadian rhythmgenetic polymorphismPTSDRNATEFtrauma

Identifiers

PMID30498461
PMCPMC6249322
OpenAlexW2901655262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.