ReviewLung Cancer (Auckland, N.Z.)2018
Silicosis and lung cancer: current perspectives.
Review in Lung Cancer (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- AWMF S2k Guideline: Diagnosis and Assessment of Lung Disease Caused by Occupational Silica Dust Exposure (Silicosis) - Disease No. 4101 as per Occupational Diseases Ordinance (BKV) Annex 1.Respiration; international review of thoracic diseases · 2026Guideline
- Systematic review of the epidemiological evidence of associations between quantified occupational exposure to respirable crystalline silica and the risk of silicosis and lung cancer.Frontiers in public health · 2025Pooled it
- Artificial Stone Associated Silicosis: A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- The hidden hazards of clay: a qualitative exploration of silica exposure and well-being in ceramic art studios.International journal of qualitative studies on health and well-being · 2026Article
- Article
- Probabilistic risk assessment of occupational exposure to respirable crystalline silica among ceramic workers in an industrial town in Iran: a Monte Carlo simulation approach.Scientific reports · 2026Article
- Pulmonary inflammatory and fibrogenic responses in rats following intratracheal instillation of dusts from natural and engineered stones.Journal of toxicology and environmental health. Part A · 2026Article
- Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice.Nature communications · 2025Article
- Kinetic Investigation of Tobermorite Synthesis for the Recovery of Carcinogenic Respirable Crystalline Silica (RCS).ACS omega · 2025Article
- Silicosis Mimicking Lung Malignancy: A Case Series.Respirology case reports · 2025Article
- Global scenario of silica-associated diseases: A review on emerging pathophysiology of silicosis and potential therapeutic regimes.Toxicology reports · 2025Review
- Applying Finite Mixture Models to Quantify Respirable Dust Mass in Coal and Metal-Nonmetal Mines Using Fourier Transform Infrared Spectroscopy.Applied spectroscopy · 2025Article
- The Influence of Gold Nanoparticles Addition on Sugarcane Leaves-Derived Silica Xerogel Catalyst for the Production of Biodiesel.Gels (Basel, Switzerland) · 2025Article
- Risk characterization for silica-related silicosis and lung cancer in communities adjacent to sand and gravel extraction facilities: examining limitations in our current risk methods.Frontiers in public health · 2025Article
- Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis.Science advances · 2024Article
- Article
- Prevalence and determinants of evidence of silicosis and impaired lung function among small scale tanzanite miners and the peri-mining community in northern Tanzania.PLOS global public health · 2024Article
- Article
- Silico-tuberculosis amidst COVID-19 pandemic: global scenario and Indian perspective.Annals of medicine and surgery (2012) · 2023Review
- Animal models of silicosis: fishing for new therapeutic targets and treatments.European respiratory review : an official journal of the European Respiratory Society · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
"Silica" refers to crystalline particles formed by the combination of silicon with oxygen. Inhalation of silica particles promotes the development of pulmonary fibrosis that over prolonged periods increases the risk of lung cancer. The International Agency for Research on Cancer (IARC) classified crystalline silica as a human carcinogen in 1997. This categorization was questioned due to 1) the absence of dose-response findings, 2) the presence of confounding variables that complicated interpretation of the data and 3) potential selection bias for compensated silicosis. Yet, recent epidemiologic studies strongly support the conclusion that silica exposure increases the risk of lung cancer in humans independent of confounding factors including cigarette smoke. Based on this evidence, the US Occupational Safety and Health Administration (OSHA) lowered the occupational exposure limit for crystalline silica from 0.1 to 0.05 mg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.