Evidence map›Paper›PMID 30498338›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

What is the impact of GOLD 2017 recommendations in primary care? - a descriptive study of patient classifications, treatment burden and costs.

Alicia Gayle, Scott Dickinson, Kevin Morris, Chris Poole, Alexander G Mathioudakis, Jørgen Vestbo

Erratum issuedAbstract readComparative Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. InhaledEuropean respiratory review : an official journal of the European Respiratory Society · 2024
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  18. Does Evaluation and Management of COPD Follow Therapeutic Strategy Recommendations?Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alicia GayleMarket Access, Boehringer Ingelheim Ltd, Bracknell, UK, alicia.gayle@boehringer-ingelheim.com.
Scott DickinsonMedical and Scientific Affairs, Boehringer Ingelheim Ltd, Bracknell, UK.
Kevin MorrisMarket Access, Boehringer Ingelheim Ltd, Bracknell, UK, alicia.gayle@boehringer-ingelheim.com.
Chris PooleMarket Access, Boehringer Ingelheim Ltd, Bracknell, UK, alicia.gayle@boehringer-ingelheim.com.
Alexander G MathioudakisDivision of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.
Jørgen VestboDivision of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe changes in grading of disease severity and treatment recommendations for patients with COPD in the 2017 GOLD strategy may present an opportunity for reducing treatment burden for the patients and costs to the health care system. The aim of this study was to assess the implications of the GOLD 2017 grading system in terms of change in distribution across GOLD groups A-D for existing patients in UK primary care and estimate the potential cost savings of implementing GOLD 2017 treatment recommendations in UK primary care. PATIENTS AND

methodsUsing electronic health record data from the Clinical Practice Research Datalink (CPRD), patients aged ≥35 years with spirometry-confirmed COPD, receiving care during 2016, were included. The cohort was graded according to the GOLD 2017 groups (A-D), and treatment costs were calculated, according to corresponding recommendations, to observe the difference in actual vs predicted costs.

resultsWhen applying GOLD 2013 criteria, less than half of the cohort (46%) was assigned to GOLD A or B, as compared to 86% when applying the GOLD 2017 grading. The actual mean annual maintenance treatment cost was £542 per patient vs a predicted £389 for treatment according to the 2017 GOLD strategy.

conclusionThere is a potential to make significant cost savings by implementing the grading and treatment recommendations from the 2017 GOLD strategy.

Indexed as

Drug CostsAdrenal Cortex HormonesAdultAgedAged, 80 and overBronchodilator AgentsCross-Sectional StudiesDatabases, FactualDecision Support TechniquesElectronic Health RecordsFemaleHealth StatusHealth Status IndicatorsHumansLungMaleAdrenal Cortex HormonesBronchodilator AgentsCOPDeconomicsGOLDseverity

Identifiers

PMID30498338
PMCPMC6207393

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.