Evidence map›Paper›PMID 30498201›Full record

ReviewMucosal immunology2019

Tipping the balance: inhibitory checkpoints in intestinal homeostasis.

Maria E Joosse, Iris Nederlof, Lucy S K Walker, Janneke N Samsom

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Mucosal immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation.International journal of molecular sciences · 2020
    Review
  7. Review
  8. Article
  9. Review
  10. Evaluation of immunologic and intestinal effects in rats administered an E 171-containing diet, a food grade titanium dioxide (TiOFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Maria E JoosseLaboratory of Pediatrics, Division Gastroenterology and Nutrition, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.
Iris NederlofDivision of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Lucy S K WalkerInstitute of Immunity & Transplantation, UCL Division of Infection & Immunity, Royal Free Campus, London, UK.
Janneke N SamsomLaboratory of Pediatrics, Division Gastroenterology and Nutrition, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands. j.samsom@erasmusmc.nl.
Erasmus MC · NLThe Netherlands Cancer Institute · NLUniversity College London · GB

Funding

Medical Research Council MR/N001435/1
6 · The paper itself

Abstract

The small intestinal and colonic lamina propria are populated with forkhead box P3 (FOXP3)

Indexed as

AnimalsAntibodies, MonoclonalCTLA-4 AntigenForkhead Transcription FactorsHomeostasisHumansImmune ToleranceImmunotherapyInflammatory Bowel DiseasesIntestinal MucosaIntestinesLymphocyte ActivationProgrammed Cell Death 1 ReceptorT-Lymphocytes, RegulatoryAntibodies, MonoclonalCTLA-4 AntigenCTLA4 protein, humanForkhead Transcription FactorsFOXP3 protein, humanPDCD1 protein, humanProgrammed Cell Death 1 Receptor

Identifiers

PMID30498201
OpenAlexW2903080897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.