Evidence map›Paper›PMID 30497812›Full record

ArticleSurgery2019

A statewide comparison of opioid prescribing in teaching versus nonteaching hospitals.

David C Cron, Charles Hwang, Hsou M Hu, Jay S Lee, James M Dupree, John D Syrjamaki, Kevin C Chung, Chad M Brummett, Michael J Englesbe, Jennifer F Waljee

Abstract readComparative Study
In one paragraph

Article in Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Opioid prescribing patterns following surgical interventions for benign prostatic hyperplasia.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Surgeon experience and opioid prescribing.American journal of surgery · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

David C CronDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Charles HwangDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Hsou M HuDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Jay S LeeDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
James M DupreeDepartment of Urology, University of Michigan Medical School, Ann Arbor.
John D SyrjamakiDepartment of Urology, University of Michigan Medical School, Ann Arbor.
Kevin C ChungDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Chad M BrummettDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor.
Michael J EnglesbeDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Jennifer F WaljeeDepartment of Surgery, University of Michigan Medical School, Ann Arbor. Electronic address: filip@med.umich.edu.
University of Michigan · US

Funding

University of Michigan Surgical Oncology Research Training ProgramT32CA009672 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACQUELINE SARA JERUSS, WEIPING ZOU · 1991 to 2026
$6.0M
oPIOIDS: Prevention of Iatrogenic Opioid Dependence after SurgeryR01DA042859 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRUMMETT, CHAD M, WALJEE, JENNIFER FILIP · 2017 to 2021
$3.6M
Evidence-Based Research in Hand SurgeryK24AR053120 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHUNG, KEVIN C · 2008 to 2018
$1.6M
NCI NIH HHS T32 CA009672NIAMS NIH HHS K24 AR053120NIDA NIH HHS R01 DA042859
6 · The paper itself

Abstract

backgroundPostoperative opioid prescribing is often excessive, but the differences in opioid prescribing between teaching hospitals and nonteaching hospitals is not well understood. Given the workload of surgical training and frequent turnover of prescribers on surgical services, we hypothesized that postoperative opioid prescribing would be higher among teaching compared with nonteaching hospitals. STUDY

designWe used insurance claims from a statewide quality collaborative in Michigan to identify 17,075 opioid-naïve patients who underwent 22 surgical procedures across 76 hospitals from 2012 to 2016. Our outcomes included the following: (1) the amount of opioid prescribed for the initial postoperative prescription in oral morphine equivalents and (2) high-risk prescribing in the 30 days after surgery (high daily dose [≥ 100 oral morphine equivalents], new long-acting/extended-release opioid, overlapping prescriptions, or concurrent benzodiazepine prescription). Teaching hospital status was obtained from the 2014 American Hospital Association survey. Multilevel regression was used to adjust for patient and procedural factors and to perform reliability adjustment.

resultsThe amount of opioid prescribed per initial opioid prescription varied 4.7-fold across all hospitals from 130 oral morphine equivalents to 616 oral morphine equivalents. Patients discharged from teaching hospitals filled larger initial opioid prescriptions overall compared with nonteaching hospitals (251 oral morphine equivalents versus 232 oral morphine equivalents; P = .026). Teaching hospitals had higher risk-adjusted rates of high-risk prescribing compared with nonteaching hospitals (13.7% vs 10.3%; P = .034).

conclusionIn Michigan, surgical patients discharged from teaching hospitals received significantly larger postoperative opioid prescriptions and had higher rates of high-risk prescribing compared with nonteaching hospitals. All hospitals, and particularly teaching institutions, should ensure that adequate resources are devoted to facilitating safe postoperative opioid prescribing.

Indexed as

Hospitals, TeachingAdultAnalgesics, OpioidDrug PrescriptionsFemaleHumansMaleMiddle AgedPostoperative PainAnalgesics, Opioid

Identifiers

PMID30497812
PMCPMC7091517
OpenAlexW2903331311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.