ArticleThe Journal of pediatrics2019
Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity.
Article in The Journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Shared Determinants of Poor Sleep, Obesity and Adiposity in Adolescents Aged 8-18-Years: A Systematic Review.Journal of sleep research · 2025Pooled it
- Sleep timing and health indicators in children and adolescents: a systematic review.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2022Pooled it
- Sleep loss as a cardiometabolic risk factor: a narrative review of clinical and public health implications.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Review
- Variable Morning Melatonin Profiles Limit Determination of Dim-Light Melatonin Offset in Preschool-Aged Children.Journal of biological rhythms · 2026Article
- Neuromodulation using Bioelectronics-enabled therapies to combat insulin resistance and its comorbidities.Journal of diabetes and metabolic disorders · 2026Review
- Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures.Sleep medicine · 2026Article
- Late evening room light and sleep restriction reduces the ability of bright morning light to phase advance adolescents' circadian clocks.Scientific reports · 2026Article
- Loneliness, problematic digital media use, and nutritional-metabolic vulnerability in adolescents from single-parent households: an integrative review of eating- and sleep-related pathways.Frontiers in nutrition · 2026Review
- Sleep Duration and Timing in Relation to BMI and Readiness to Change Lifestyle Behaviors: Results From a Pediatric Weight Management Clinic.Clinical pediatrics · 2025Article
- Sleep and circadian rhythms in delayed sleep-wake phase disorder: Phenotypic differences between patients with and without comorbid depression.Journal of sleep research · 2025Article
- Article
- Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study.Journal of ovarian research · 2025Article
- Sex Differences in Circadian Timing and Biological Night in Adolescents.Journal of biological rhythms · 2025Article
- Home-based dim light melatonin onset assessment among adults with obesity: feasibility and procedural considerations.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Sleep conditions and sleep hygiene behaviors in early pregnancy are associated with gestational diabetes mellitus: A propensity-score matched study.Sleep & breathing = Schlaf & Atmung · 2024Article
- Racial and ethnic sleep health disparities in adolescents and risk for type 2 diabetes: a narrative review.Annals of medicine · 2024Review
- Weight-neutral approach and later sleep midpoint in adolescents with "emerging polycystic ovary syndrome phenotype" as vehicles for sustainable weight loss.F&S reports · 2024Article
- Are Adolescent Athletes Sleeping Enough? An Observational Study of Sleep Parameters during Schooldays and Holidays.Children (Basel, Switzerland) · 2024Article
- Associations between circadian alignment and cognitive functioning in a nationally representative sample of older adults.Scientific reports · 2024Article
- Influence of circadian phase and extended wakefulness on glucose levels during forced desynchrony.Sleep health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo examine the relationship between insulin resistance (IR) and sleep/circadian health in overweight/obese adolescents. We hypothesized that insufficient and delayed sleep would be associated with IR in this population. STUDY
designThirty-one adolescents (mean age, 16.0 ± 1.4 years; 77% female) with body mass index ≥90th percentile for age/sex were recruited from outpatient clinics at a children's hospital. Participants underwent 1 week of objective home sleep monitoring with wrist actigraphy during the academic year. A 3-hour oral glucose tolerance test was conducted, followed by in-laboratory salivary dim-light melatonin sampling every 30-60 minutes from 5 p.m. to noon the next day. Regression analyses between sleep and circadian variables with IR were examined.
resultsLonger sleep time and time in bed on weekends and weekdays and earlier weekday bedtime were significantly associated with better insulin sensitivity. Participants who obtained less than the median duration of sleep per night (6.6 hours) had evidence of IR with compensatory insulin secretion compared with those obtaining ≥6.6 hours of sleep. A wider phase angle between bedtime and melatonin onset, indicating a later circadian timing of sleep onset, was significantly associated with IR.
conclusionsShort sleep duration, later weekday bedtime, and later circadian timing of sleep were associated with IR in a cohort of adolescents with overweight/obesity during the school year. Further research is needed to better understand the physiology underlying these observations and to evaluate the impact of improved sleep and circadian health on metabolic health in this at-risk population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.