Evidence map›Paper›PMID 30497449›Full record

ArticleBMC oral health2018

Oral health experiences of individuals with Rett syndrome: a retrospective study.

Y Y L Lai, K Wong, N M King, J Downs, H Leonard

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  3. Rett syndrome in Ireland: a demographic study.Orphanet journal of rare diseases · 2024
    Article
  4. Article
  5. Enablers and barriers in dental attendance in Rett syndrome: an international observational study.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2022
    Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Y Y L LaiDepartment of Paediatric Dentistry, School of Dentistry, The University of Western Australia, Perth, WA, Australia.
K WongTelethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
N M KingDepartment of Paediatric Dentistry, School of Dentistry, The University of Western Australia, Perth, WA, Australia.
J DownsTelethon Kids Institute, The University of Western Australia, Perth, WA, Australia.
H LeonardTelethon Kids Institute, The University of Western Australia, Perth, WA, Australia. Helen.leonard@telethonkids.org.au.ORCID 0000-0001-6405-5834
The Kids Research Institute Australia · AUThe University of Western Australia · AU

Funding

National Health and Medical Research Council 1004384National Health and Medical Research Council 1117105National Health and Medical Research Council 303189NIH HHS 5R01HD043100-05
6 · The paper itself

Abstract

backgroundThere is relatively little literature on the oral health experiences of individuals with Rett syndrome. This study described the incidence of dental extractions and restorations in a population-based cohort, according to a range of demographic and clinical factors. The association between bruxism and age was also investigated.

methodsExisting questionnaire data in the population-based Australian Rett Syndrome Database for the years 2004, 2006, 2009 or 2011 on genetically confirmed female cases (n = 242) were analysed.

resultsThe incidence rate of restorations and extractions were 6.8 per 100 person years (py) and 9.3 per 100 py respectively. The incidence of extractions decreased with increasing levels of income. Compared to those with a C-terminal mutation, the incidence rate of extraction was higher for those with large deletions (Incidence Rate Ratio (IRR) 4.93; 95% CI 1.46-16.7, p = 0.01). There was a 5% decrease in the risk of frequent bruxism for every one-year increase in age (Risk Ratio 0.95; 95% CI 0.94-0.97).

conclusionsSocial advantage may provide some protection for dental health in individuals with Rett syndrome. Those with more severe genotypes seemed to have poorer oral health outcomes.

Indexed as

Oral HealthAdolescentAdultAustraliaBruxismChildChild, PreschoolDatabases, FactualDental Restoration, PermanentDevelopmental DisabilitiesFemaleHumansIncidenceMutationRetrospective StudiesRett SyndromeDental manifestationDevelopmental disabilityMECP2Oral health experienceRare disorderRett syndrome

Identifiers

PMID30497449
PMCPMC6267076
OpenAlexW2902499602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.