Evidence map›Paper›PMID 30497448›Full record

ArticleBMC cancer2018

Assessment of metabolic patterns and new antitumoral treatment in osteosarcoma xenograft models by [

María Collantes, Naiara Martínez-Vélez, Marta Zalacain, Lucia Marrodán, Margarita Ecay, María José García-Velloso, Marta María Alonso, Ana Patiño-García, Iván Peñuelas

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Review
  4. International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

María CollantesServicio de Medicina Nuclear, Clínica Universidad de Navarra, Avenida Pío XII, 36 31008, Pamplona, Spain.
Naiara Martínez-VélezDepartamento de Pediatría, Clínica Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
Marta ZalacainDepartamento de Pediatría, Clínica Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
Lucia MarrodánDepartamento de Pediatría, Clínica Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
Margarita EcaySmall Animal Imaging Research Unit, CIMA, Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
María José García-VellosoServicio de Medicina Nuclear, Clínica Universidad de Navarra, Avenida Pío XII, 36 31008, Pamplona, Spain.
Marta María AlonsoDepartamento de Pediatría, Clínica Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
Ana Patiño-GarcíaDepartamento de Pediatría, Clínica Universidad de Navarra, Avenida Pío XII, 31008, Pamplona, Spain.
Iván PeñuelasServicio de Medicina Nuclear, Clínica Universidad de Navarra, Avenida Pío XII, 36 31008, Pamplona, Spain. ipenuelas@unav.es.ORCID http://orcid.org/0000-0001-8008-976X
Navarre Institute of Health Research · ESClinica Universidad de Navarra · ESUniversidad de Navarra · ES

Funding

Basque Foundation for Health Research BIOEF, BIO13/CI/005H2020 Marie Skłodowska-Curie Actions IRG270459Instituto de Salud Carlos III PI16/00066Ministerio de Ciencia e Innovación (ES) IEDI-2015-00638
6 · The paper itself

Abstract

backgroundOsteosarcoma is the most common malignant bone tumor in children and young adults that produces aberrant osteoid. The aim of this study was to assess the utility of 2-deoxy-2-[18F-] fluoro-D-glucose ([

methodsOrthotopic osteosarcoma murine models were created by the injection of 143B and 531MII cell lines. [

resultsThe metabolic pattern of tumors was different between both orthotopic models. All tumors showed [

conclusionsPET studies demonstrated that the different osteosarcoma xenograft models developed tumors with diverse metabolic patterns that can be described by multitracer PET studies. Since not all tumors produced abundant osteoid, [

Indexed as

Energy MetabolismFluorine RadioisotopesFluorodeoxyglucose F18Positron-Emission TomographyAnimalsCell Line, TumorDisease Models, AnimalFemaleHumansImage Processing, Computer-AssistedMaleMiceOsteosarcomaRadiopharmaceuticalsFluorine-18Fluorine RadioisotopesFluorodeoxyglucose F18RadiopharmaceuticalsAnimal modelsOsteosarcomaPET

Identifiers

PMID30497448
PMCPMC6267920
OpenAlexW2902277778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.