ArticleBMC geriatrics2018
The deprescribing rainbow: a conceptual framework highlighting the importance of patient context when stopping medication in older people.
Article in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Are there socioeconomic inequalities in polypharmacy among older people? A systematic review and meta-analysis.BMC geriatrics · 2023Pooled it
- Polypharmacy definition and prevalence in heart failure: a systematic review.Heart failure reviews · 2022Pooled it
- Harm and Medication-Type Impact Agreement with Hypothetical Deprescribing Recommendations: a Vignette-Based Experiment with Older Adults Across Four Countries.Journal of general internal medicine · 2023Trial
- Communication as Mediator: Interprofessional Deprescribing and the RCC (Roles-Collaboration-Communication) Framework.Healthcare (Basel, Switzerland) · 2026Article
- Patient Attitudes and Factors Associated with Willingness to Deprescribe Prescribed Medications in Western Saudi Arabia: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Stakeholder Perspectives on the Use of Telehealth to Support Deprescribing for Older Patients Transitioning From the Hospital to Home Health Care.Journal of the American Geriatrics Society · 2026Article
- The Reporting and Methodological Recommendations for Observational Studies Estimating the Effects of Deprescribing Medications (REMROSE-D) ISPE-Endorsed Guidance.Pharmacoepidemiology and drug safety · 2025Article
- Deprescribing for People with Dementia: A Roadmap.Drugs & aging · 2025Review
- Metabolic Syndrome in Older Adults: Through the Lens of Institute for Healthcare Improvement's (IHI) 4Ms Framework and Social Determinants of Health.Life (Basel, Switzerland) · 2025Review
- Shared decision-making and deprescribing to support anti-thrombotic therapy (dis)continuance for persons living with cancer in their last phase of life: A realist synthesis.PLoS medicine · 2025Article
- 'Do I actually even need all these tablets?' A qualitative study exploring deprescribing decision-making for people in receipt of palliative care and their family members.Palliative medicine · 2025Article
- "Starting to think that way from the start": approaching deprescribing decision-making for people accessing palliative care - a qualitative exploration of healthcare professionals views.BMC palliative care · 2024Article
- Challenges in Deprescribing among Older Adults in Post-Acute Care Transitions to Home.Journal of the American Medical Directors Association · 2024Article
- Medication misuse and overuse in community-dwelling persons with dementia.Journal of the American Geriatrics Society · 2023Article
- Deprescribing research in nursing home residents using routinely collected healthcare data: a conceptual framework.BMC geriatrics · 2023Review
- The Barriers to Deprescription in Older Patients: A Survey of Spanish Clinicians.Healthcare (Basel, Switzerland) · 2023Article
- Medication work among nonagenarians: a qualitative study of the Newcastle 85+ cohort participants at 97 years old.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Article
- Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of thePrimary health care research & development · 2023Article
- Disentangling concepts of inappropriate polypharmacy in old age: a scoping review.BMC public health · 2023Article
- Potentially inappropriate prescribing in older adults with cancer receiving specialist palliative care: a retrospective observational study.International journal of clinical pharmacy · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The area of "deprescribing" has rapidly expanded in recent years as a positive intervention to reduce inappropriate polypharmacy and improve health outcomes for (older) people with multimorbidity. While our understanding of deprescribing as a process has greatly improved and existing approaches all have patient-centered elements, there is still limited literature exploring the importance of the individual patient context in deprescribing decision-making. This is clearly an important consideration to ensure that any deprescribing approach is ethical, respectful, and successful. To address this gap in the literature, we have developed a conceptual framework in the form of a rainbow - with five different deprescribing determinants - and place the person at the center of the deprescribing process. This framework is informed by literature on patient-centered care for older people and people with multimorbidity. We illustrate the potential application of this framework to a complex patient case to highlight the importance of the different clinical, psychological, social, financial and physical deprescribing determinants, and how this approach could be adopted by those working in clinical practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.