ArticleHuman pathology2019
Contribution of the clinical information to the accuracy of the minimally invasive and the complete diagnostic autopsy.
Article in Human pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Validation of malaria-attributed deaths using verbal autopsy studies: a systematic review.Malaria journal · 2024Pooled it
- Pooled it
- The acceptability of minimally invasive tissue sampling for cause of death determination in rural South Africa: A qualitative analysis.PloS one · 2026Article
- High-risk coronary plaque of sudden cardiac death victims: postmortem CT angiographic features and histopathologic findings.International journal of legal medicine · 2024Article
- Minimally invasive autopsy - endoscopic approach to post-mortem diagnostics.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024Review
- Determination of causes of adult deaths using minimally invasive tissue sampling in Gandaki province of Nepal: a multicenter hospital-based study.European journal of medical research · 2023Article
- Survey of Clinical and Anatomic Pathology Laboratory Infrastructure in Mozambique.American journal of clinical pathology · 2021Article
- Accuracy of verbal autopsy, clinical data and minimally invasive autopsy in the evaluation of malaria-specific mortality: an observational study.BMJ global health · 2021Observational
- Safe Management Strategies in Clinical Forensic Autopsies of Confirmed COVID-19 Cases.Diagnostics (Basel, Switzerland) · 2021Article
- A single-centre, retrospective study of the incidence of invasive fungal infections during 85 years of autopsy service in Brazil.Scientific reports · 2021Article
- The evolution of minimally invasive tissue sampling in postmortem examination: a narrative review.Global health action · 2020Review
- Postmortem imaging as a complementary tool for the investigation of cardiac death.Forensic sciences research · 2019Review
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Authors and funding
32 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although autopsy diagnosis includes routinely, a thorough evaluation of all available pathological results and also of any available clinical data, the contribution of this clinical information to the diagnostic yield of the autopsy has not been analyzed. We aimed to determine to which degree the use of clinical data improves the diagnostic accuracy of the complete diagnostic autopsy (CDA) and the minimally invasive autopsy (MIA), a simplified pathological postmortem procedure designed for low-income sites. A total of 264 coupled MIA and CDA procedures (112 adults, 57 maternal deaths, 54 children, and 41 neonates) were performed at the Maputo Hospital, Mozambique. We compared the diagnoses obtained by the MIA blind to clinical data (MIAb), the MIA adding the clinical information (MIAc), and the CDA blind to clinical information (CDAb), with the results of the gold standard, the CDA with clinical data, by comparing the International Classification of Diseases, Tenth Revision codes and the main diagnostic classes obtained with each evaluation strategy (MIAb, MIAc, CDAb, CDAc). The clinical data increased diagnostic coincidence to the MIAb with the gold standard in 30 (11%) of 264 cases and modified the CDAb diagnosis in 20 (8%) of 264 cases. The increase in concordance between MIAb and MIAc with the gold standard was significant in neonatal deaths (κ increasing from 0.404 to 0.618, P = .0271), adult deaths (κ increasing from 0.732 to 0.813, P = .0221), and maternal deaths (κ increasing from 0.485 to 0.836, 0.;P < .0001). In conclusion, the use of clinical information increases the precision of MIA and CDA and may strengthen the performance of the MIA in resource-limited settings.
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