Evidence map›Paper›PMID 30496533›Full record

Trial reportSleep2019

Cognitive behavioral treatments for insomnia and pain in adults with comorbid chronic insomnia and fibromyalgia: clinical outcomes from the SPIN randomized controlled trial.

Christina S McCrae, Jacob Williams, Daniela Roditi, Ryan Anderson, Jennifer M Mundt, Mary Beth Miller, Ashley F Curtis, Lori B Waxenberg, Roland Staud, Richard B Berry and 1 more

2 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sleep, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 10 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02001077 nacompletednot on this map

Sleep and Pain Interventions in Fibromyalgia: Hyperalgesia and Central Sensitization

TypeinterventionalSponsorUniversity of FloridaRan2009 to 2013Enrolled113ConditionsInsomnia, FibromyalgiaArmsCognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Pain (CBT-P)
NCT06345872 narecruitingnot on this mapstarted 2024, after this paper: background citation

SPIN Opioid: Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

TypeinterventionalSponsorUniversity of South FloridaRan2024 to 2028Enrolled165ConditionsChronic Pain, Chronic Insomnia, Opioid UseArmsCBT-I, Treatment as usual, Tapered Withdrawal
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 10 syntheses or guidelines pooled it, 125 citations in OpenAlex.

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  15. Cannabis use as a moderator of cognitive behavioral therapy for insomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Christina S McCraeDepartment of Psychiatry, University of Missouri - Columbia, Columbia, MO.
Jacob WilliamsDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
Daniela RoditiDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
Ryan AndersonDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
Jennifer M MundtDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
Mary Beth MillerDepartment of Psychiatry, University of Missouri - Columbia, Columbia, MO.
Ashley F CurtisDepartment of Psychiatry, University of Missouri - Columbia, Columbia, MO.
Lori B WaxenbergDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
Roland StaudDepartment of Rheumatology and Clinical Immunology, University of Florida, Gainesville, FL.
Richard B BerryDivision of Pulmonary, Critical Care and Sleep Medicine, Gainesville, FL.
Michael E RobinsonDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL.
University of Florida Health · USUniversity of Missouri · USUniversity of Florida · US

Funding

Sleep and Pain Interventions in Fibromyalgia: Hyperalgesia and Central SensitizatR01AR055160 · NIAMS · UNIVERSITY OF FLORIDA · PI MCCRAE, CHRISTINA S · 2008 to 2012
$1.9M
NIAMS NIH HHS R01 AR055160
6 · The paper itself

Abstract

STUDY

objectivesTo examine the effects of cognitive behavioral treatments for insomnia (CBT-I) and pain (CBT-P) in patients with comorbid fibromyalgia and insomnia.

methodsOne hundred thirteen patients (Mage = 53, SD = 10.9) were randomized to eight sessions of CBT-I (n = 39), CBT-P (n = 37), or a waitlist control (WLC, n = 37). Primary (self-reported sleep onset latency [SOL], wake after sleep onset [WASO], sleep efficiency [SE], sleep quality [SQ], and pain ratings) and secondary outcomes (dysfunctional beliefs and attitudes about sleep [DBAS]; actigraphy and polysomnography SOL, WASO, and SE; McGill Pain Questionnaire; Pain Disability Index; depression; and anxiety) were examined at posttreatment and 6 months.

resultsMixed effects analyses revealed that both treatments improved self-reported WASO, SE, and SQ relative to control at posttreatment and follow-up, with generally larger effect sizes for CBT-I. DBAS improved in CBT-I only. Pain and mood improvements did not differ by group. Clinical significance analyses revealed the proportion of participants no longer reporting difficulties initiating and maintaining sleep was higher for CBT-I posttreatment and for both treatments at 6 months relative to control. Few participants achieved >50% pain reductions. Proportion achieving pain reductions of >30% (~1/3) was higher for both treatments posttreatment and for CBT-I at 6 months relative to control.

conclusionsCBT-I and CBT-P improved self-reported insomnia symptoms. CBT-I prompted improvements of larger magnitude that were maintained. Neither treatment improved pain or mood. However, both prompted clinically meaningful, immediate pain reductions in one third of patients. Improvements persisted for CBT-I, suggesting that CBT-I may provide better long-term pain reduction than CBT-P. Research identifying which patients benefit and mechanisms driving intervention effects is needed. CLINICAL TRIAL: Sleep and Pain Interventions in Fibromyalgia (SPIN), clinicaltrials.gov, NCT02001077.

Indexed as

ActigraphyAdultAffectAnxietyCognitionCognitive Behavioral TherapyComorbidityDepressionFemaleFibromyalgiaHumansMaleMiddle AgedPainPain ManagementPain MeasurementCBTcognitive behavioral treatmentscomorbid chronic insomniafibromyalgiapainsleep

Identifiers

PMID30496533
PMCPMC6424087
OpenAlexW2903063465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.