Evidence map›Paper›PMID 30496295›Full record

ArticlePloS one2018

Short-term prognosis of emergently hospitalized dialysis-independent chronic kidney disease patients: A nationwide retrospective cohort study in Japan.

Hiroaki Kikuchi, Eiichiro Kanda, Takayasu Mori, Hidehiko Sato, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Eisei Sohara, Tomokazu Okado, Shinichi Uchida and 2 more

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroaki KikuchiDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Eiichiro KandaMedical Science, Kawasaki Medical School, Okayama, Japan.
Takayasu MoriDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Hidehiko SatoDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Soichiro IimoriDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Naohiro NomuraDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Shotaro NaitoDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Eisei SoharaDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Tomokazu OkadoDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Shinichi UchidaDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.ORCID 0000-0002-1894-0290
Tatemitsu RaiDepartment of Nephrology, Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.ORCID 0000-0001-7695-778X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with chronic kidney disease (CKD), low body mass index (BMI) is associated with high mortality. This relationship in emergently hospitalized CKD patients is unknown. We investigated the association between obesity and short-term mortality in emergently admitted patients with dialysis-independent CKD (DI-CKD) with and without infection. This retrospective cohort study examined Diagnosis Procedure Combination data of 26103 emergently hospitalized DI-CKD patients. Patients were divided into 8 groups according to their BMI and the presence of infectious diseases. The primary outcome was in-hospital death within 100 days. Cox proportional hazards models adjusted for baseline characteristics showed that low BMI was associated with the outcome both in infected and in non-infected patients (reference group as non-infected and medium BMI [24-26 kg/m2] group): infected and the lowest BMI (≤20 kg/m2) group, hazard ratio (HR) 1.82 (95% confidence interval 1.51, 2.19); non-infected and the lowest BMI group, 1.39 (1.16, 1.67). When patients were stratified according to presence of diabetes mellitus (DM), patients with DM showed that low BMI was associated with the outcome both in infected and in non-infected patients, whereas in non-DM patients, this relationship was attenuated in the non-infected group. For emergently hospitalized CKD patients with infection, high BMI was associated with lower mortality irrespective of the DM status. For non-infected patients, the effects of obesity for in-hospital mortality were modified by the DM status.

Indexed as

AdultAgedBody Mass IndexCommunicable DiseasesDiabetes ComplicationsEmergency Medical ServicesFemaleHospitalizationHumansJapanMaleMiddle AgedObesityPrognosisProportional Hazards ModelsRenal Dialysis

Identifiers

PMID30496295
PMCPMC6264841

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.