Evidence map›Paper›PMID 30496006›Full record

ArticleAmerican journal of public health2019

Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings.

Willem K Scholten, Ann-Eva Christensen, Anne Estrup Olesen, Asbjørn Mohr Drewes

Abstract read
In one paragraph

Article in American journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Willem K ScholtenWillem K. Scholten is with Mech-Sense, Aalborg University Hospital, Aalborg, Denmark, and Willem Scholten Consultancy, Lopik, the Netherlands. Ann-Eva Christensen is with the Unit of Epidemiology and Biostatistics, Aalborg University Hospital. Anne Estrup Olesen and Asbjørn Mohr Drewes are with Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, and Department of Clinical Medicine, Aalborg University, Aalborg. Anne Estrup Olesen is also with Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ann-Eva ChristensenWillem K. Scholten is with Mech-Sense, Aalborg University Hospital, Aalborg, Denmark, and Willem Scholten Consultancy, Lopik, the Netherlands. Ann-Eva Christensen is with the Unit of Epidemiology and Biostatistics, Aalborg University Hospital. Anne Estrup Olesen and Asbjørn Mohr Drewes are with Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, and Department of Clinical Medicine, Aalborg University, Aalborg. Anne Estrup Olesen is also with Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Anne Estrup OlesenWillem K. Scholten is with Mech-Sense, Aalborg University Hospital, Aalborg, Denmark, and Willem Scholten Consultancy, Lopik, the Netherlands. Ann-Eva Christensen is with the Unit of Epidemiology and Biostatistics, Aalborg University Hospital. Anne Estrup Olesen and Asbjørn Mohr Drewes are with Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, and Department of Clinical Medicine, Aalborg University, Aalborg. Anne Estrup Olesen is also with Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Asbjørn Mohr DrewesWillem K. Scholten is with Mech-Sense, Aalborg University Hospital, Aalborg, Denmark, and Willem Scholten Consultancy, Lopik, the Netherlands. Ann-Eva Christensen is with the Unit of Epidemiology and Biostatistics, Aalborg University Hospital. Anne Estrup Olesen and Asbjørn Mohr Drewes are with Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, and Department of Clinical Medicine, Aalborg University, Aalborg. Anne Estrup Olesen is also with Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opioid analgesics are the mainstay for treatment of moderate and severe pain but, in many countries, the consumption of these medicines is inadequate. Over time, various groups have published opioid analgesic metrics, including authors from the World Health Organization. They linked consumption to a level considered adequate based on the actual consumption in developed countries. In this study, we present our current results on the adequacy of opioid analgesic consumption. We included statistics for 18 controlled opioid medicines that are primarily used as analgesics, and we developed the Adequacy of Opioid Consumption (AOC) Index. The average of the 20 most developed countries for 2015 is set as equal to an AOC Index of 100. An AOC Index of 100 or higher is considered adequate consumption. The average opioid analgesic consumption of the top-20 countries of the Human Development Index increased from 84 morphine milligram equivalents per capita (2000) to 256 morphine milligram equivalents per capita (2015). The extremes we found for 2015 were Germany (AOC Index: 304) and Nigeria (AOC Index: 0.0069). These extremes differ by 44 000 times. Adequacy of opioid analgesic consumption continues to be problematic around the world.

Indexed as

Pain ManagementAnalgesics, OpioidDeveloping CountriesDrug PrescriptionsGermanyGlobal HealthHealth Services AccessibilityHumansNigeriaPainWorld Health OrganizationAnalgesics, Opioid

Identifiers

PMID30496006
PMCPMC6301424

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.